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. 1987 May;386:311–331. doi: 10.1113/jphysiol.1987.sp016536

Integrative processing of vibratory information in cat dorsal column nuclei neurones driven by identified sensory fibres.

D G Ferrington 1, M J Rowe 1, R P Tarvin 1
PMCID: PMC1192464  PMID: 3681713

Abstract

1. In decerebrate or anaesthetized cats, the vibration-induced responses of dorsal column nuclei neurones were examined, first, when their input came from simultaneously recorded pairs or other combinations of identified Pacinian corpuscle (P.c.) afferent fibres of the interosseous nerve, and secondly, when different convergent sets of P.c. fibres were engaged by footpad vibration. 2. Suprathreshold actions were observed on individual dorsal column nuclei neurones from two or more identified P.c. fibres. Recruitment of these convergent fibres usually led to summation in the dorsal column nuclei neurone as reflected in higher response levels compared with those evoked by single-fibre inputs. 3. When the input was increased from one to two or more identified P.c. fibres the dorsal column nuclei neurones could retain a single, dominant phase of response to high-frequency (greater than 100 Hz) vibration even though these fibres, in isolation, evoked responses in the target neurone at substantially different latencies. However, on average, phase locking was significantly tighter in response to single-fibre input than to multiple P.c.-fibre input. 4. Dorsal column nuclei neurones were also able to retain phase-locked responses to high-frequency vibration when phase differences between different convergent inputs were systematically introduced to alter the degree of synchrony in the activity arriving over convergent, identified P.c. fibres. 5. When the input to dorsal column nuclei neurones came from the skin it was found that with the recruitment of two converging sets of P.c. fibres the dorsal column nuclei neurones were able to retain phase-locked responses to high-frequency vibration even when phase shifts were introduced between the two sets of P.c. inputs. 6. In conclusion, the observed integrative processing by dorsal column nuclei neurones of vibration-induced inputs arriving over identified, convergent P.c. fibres, or sets of P.c. fibres, is consistent with our hypothesis that the retention of phase-locked responses to vibration at frequencies greater than or equal to 100 Hz may reflect the functional domination of the target neurone by just one or a few of its convergent input fibres.

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Selected References

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  1. ANDERSEN P., ECCLES J. C., OSHIMA T., SCHMIDT R. F. MECHANISMS OF SYNAPTIC TRANSMISSION IN THE CUNEATE NUCLEUS. J Neurophysiol. 1964 Nov;27:1096–1116. doi: 10.1152/jn.1964.27.6.1096. [DOI] [PubMed] [Google Scholar]
  2. Bennett R. E., Ferrington D. G., Rowe M. Tactile neuron classes within second somatosensory area (SII) of cat cerebral cortex. J Neurophysiol. 1980 Feb;43(2):292–309. doi: 10.1152/jn.1980.43.2.292. [DOI] [PubMed] [Google Scholar]
  3. Brown A. G., Franz D. N. Responses of spinocervical tract neurones to natural stimulation of identified cutaneous receptors. Exp Brain Res. 1969;7(3):231–249. doi: 10.1007/BF00239031. [DOI] [PubMed] [Google Scholar]
  4. Bystrzycka E., NAil B. S., Rowe M. Inhibition of cuneate neurones: its afferent source and influence on dynamically sensitive "tactile" neurones. J Physiol. 1977 Jun;268(1):251–270. doi: 10.1113/jphysiol.1977.sp011856. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Connor K. M., Ferrington D. G., Rowe M. J. Tactile sensory coding during development: signaling capacities of neurons in kitten dorsal column nuclei. J Neurophysiol. 1984 Jul;52(1):86–98. doi: 10.1152/jn.1984.52.1.86. [DOI] [PubMed] [Google Scholar]
  6. Douglas P. R., Ferrington D. G., Rowe M. Coding of information about tactile stimuli by neurones of the cuneate nucleus. J Physiol. 1978 Dec;285:493–513. doi: 10.1113/jphysiol.1978.sp012585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Ferrington D. G., Hora M. O., Rowe M. J. Functional maturation of tactile sensory fibers in the kitten. J Neurophysiol. 1984 Jul;52(1):74–85. doi: 10.1152/jn.1984.52.1.74. [DOI] [PubMed] [Google Scholar]
  8. Ferrington D. G., Horniblow S., Rowe M. J. Temporal patterning in the responses of gracile and cuneate neurones in the cat to cutaneous vibration. J Physiol. 1987 May;386:277–291. doi: 10.1113/jphysiol.1987.sp016534. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ferrington D. G., Rowe M. J. Functional capacities of tactile afferent fibres in neonatal kittens. J Physiol. 1980 Oct;307:335–353. doi: 10.1113/jphysiol.1980.sp013438. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ferrington D. G., Rowe M. J. Specificity of connections and tactile coding capacities in cuneate nucleus of the neonatal kitten. J Neurophysiol. 1982 Apr;47(4):622–640. doi: 10.1152/jn.1982.47.4.622. [DOI] [PubMed] [Google Scholar]
  11. Ferrington D. G., Rowe M. J., Tarvin R. P. Actions of single sensory fibres on cat dorsal column nuclei neurones: vibratory signalling in a one-to-one linkage. J Physiol. 1987 May;386:293–309. doi: 10.1113/jphysiol.1987.sp016535. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Ferrington D. G., Rowe M. Differential contributions to coding of cutaneous vibratory information by cortical somatosensory areas I and II. J Neurophysiol. 1980 Feb;43(2):310–331. doi: 10.1152/jn.1980.43.2.310. [DOI] [PubMed] [Google Scholar]
  13. GORDON G., JUKES M. G. DUAL ORGANIZATION OF THE EXTEROCEPTIVE COMPONENTS OF THE CAT'S GRACILE NUCLEUS. J Physiol. 1964 Sep;173:263–290. doi: 10.1113/jphysiol.1964.sp007456. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Goff G. D. Differential discrimination of frequency of cutaneous mechanical vibration. J Exp Psychol. 1967 Jun;74(2):294–299. doi: 10.1037/h0024561. [DOI] [PubMed] [Google Scholar]
  15. Greenstein J., Kavanagh P., Rowe M. J. Phase coherence in vibration-induced responses of tactile fibres associated with Pacinian corpuscle receptors in the cat. J Physiol. 1987 May;386:263–275. doi: 10.1113/jphysiol.1987.sp016533. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. HUNT C. C. On the nature of vibration receptors in the hind limb of the cat. J Physiol. 1961 Jan;155:175–186. doi: 10.1113/jphysiol.1961.sp006621. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Johnson K. O. Reconstruction of population response to a vibratory stimulus in quickly adapting mechanoreceptive afferent fiber population innervating glabrous skin of the monkey. J Neurophysiol. 1974 Jan;37(1):48–72. doi: 10.1152/jn.1974.37.1.48. [DOI] [PubMed] [Google Scholar]
  18. Mountcastle V. B., Talbot W. H., Sakata H., Hyvärinen J. Cortical neuronal mechanisms in flutter-vibration studied in unanesthetized monkeys. Neuronal periodicity and frequency discrimination. J Neurophysiol. 1969 May;32(3):452–484. doi: 10.1152/jn.1969.32.3.452. [DOI] [PubMed] [Google Scholar]
  19. PERL E. R., WHITLOCK D. G., GENTRY J. R. Cutaneous projection to second-order neurons of the dorsal column system. J Neurophysiol. 1962 May;25:337–358. doi: 10.1152/jn.1962.25.3.337. [DOI] [PubMed] [Google Scholar]
  20. Rothenberg M., Verrillo R. T., Zahorian S. A., Brachman M. L., Bolanowski S. J., Jr Vibrotactile frequency for encoding a speech parameter. J Acoust Soc Am. 1977 Oct;62(4):1003–1012. doi: 10.1121/1.381610. [DOI] [PubMed] [Google Scholar]
  21. Talbot W. H., Darian-Smith I., Kornhuber H. H., Mountcastle V. B. The sense of flutter-vibration: comparison of the human capacity with response patterns of mechanoreceptive afferents from the monkey hand. J Neurophysiol. 1968 Mar;31(2):301–334. doi: 10.1152/jn.1968.31.2.301. [DOI] [PubMed] [Google Scholar]
  22. WINTER D. L. N. GRACILIS OF CAT. FUNCTIONAL ORGANIZATION AND CORTICOFUGAL EFFECTS. J Neurophysiol. 1965 Jan;28:48–70. doi: 10.1152/jn.1965.28.1.48. [DOI] [PubMed] [Google Scholar]
  23. Willis W. D., Maunz R. A., Foreman R. D., Coulter J. D. Static and dynamic responses of spinothalamic tract neurons to mechanical stimuli. J Neurophysiol. 1975 May;38(3):587–600. doi: 10.1152/jn.1975.38.3.587. [DOI] [PubMed] [Google Scholar]

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