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. 1986 Jan;370:13–24. doi: 10.1113/jphysiol.1986.sp015919

Ventilatory drive during face immersion in man.

M R Mukhtar, J M Patrick
PMCID: PMC1192665  PMID: 3083097

Abstract

Four series of experiments have been performed in normal subjects to determine whether face immersion gives rise to a reduction in ventilatory drive. Such a response might be advantageous, like the cardiovascular components of the 'diving response', in prolonging breath-hold diving. In the first series, ventilatory drive was measured indirectly as the maximal voluntary breath-holding time, starting each breath-hold at the same alveolar partial pressures and at the same lung volume. When the face was immersed in cold water, breath-holding times were increased by 14%. The breaking point occurred at a higher alveolar PCO2 and the rate of rise of PCO2 was not affected. Control immersions in warm water had no effect. In the second and third series, subjects lay prone and breathed either air or 5% CO2 through a valve in the bottom of a bowl. Minute ventilation was measured before, during and after 5 min of face immersion in cold water. Transient hypoventilations of 13% and 10% respectively were seen, accompanied by small rises in alveolar PCO2. In control experiments, immersion of the forearm in cold water produced the opposite responses. In the fourth series, a cold wet pack was applied to the face during moderate steady-state exercise. A small irregular hypoventilation was seen, but not in control experiments when a warm pack was applied. Face temperatures fell by about 10 degrees C in these experiments. No material changes were found in the temperatures of the inspired air or of the aural canal. It is concluded that face immersion in cold water causes a modest reduction in ventilatory drive in man. This appears to be a component of the 'diving response'.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brick I. Circulatory responses to immersing the face in water. J Appl Physiol. 1966 Jan;21(1):33–36. doi: 10.1152/jappl.1966.21.1.33. [DOI] [PubMed] [Google Scholar]
  2. Burgess K. R., Whitelaw W. A. Reducing ventilatory response to carbon dioxide by breathing cold air. Am Rev Respir Dis. 1984 May;129(5):687–690. doi: 10.1164/arrd.1984.129.5.687. [DOI] [PubMed] [Google Scholar]
  3. Campbell L. B., Gooden B. A., Horowitz J. D. Cardiovascular responses to partial and total immersion in man. J Physiol. 1969 May;202(1):239–250. doi: 10.1113/jphysiol.1969.sp008807. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Caputa M., Cabanac M. Bradycardia during face cooling in man may be produced by selective brain cooling. J Appl Physiol Respir Environ Exerc Physiol. 1979 May;46(5):905–907. doi: 10.1152/jappl.1979.46.5.905. [DOI] [PubMed] [Google Scholar]
  5. Drummond P. C., Jones D. R. The initiation and maintenance of bradycardia in a diving mammal, the muskrat, Ondatra zibethica. J Physiol. 1979 May;290(2):253–271. doi: 10.1113/jphysiol.1979.sp012770. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Elsner R., Angell-James J. E., de Burgh Daly M. Carotid body chemoreceptor reflexes and their interactions in the seal. Am J Physiol. 1977 May;232(5):H517–H525. doi: 10.1152/ajpheart.1977.232.5.H517. [DOI] [PubMed] [Google Scholar]
  7. Folgering H., Olivier O. The diving response depresses ventilation in man. Bull Eur Physiopathol Respir. 1985 Mar-Apr;21(2):143–147. [PubMed] [Google Scholar]
  8. Gooden B. A., Lehman R. G., Pym J. Role of the face in the cardiovascular responses to total immersion. Aust J Exp Biol Med Sci. 1970 Dec;48(6):687–690. doi: 10.1038/icb.1970.66. [DOI] [PubMed] [Google Scholar]
  9. James J. E., Daly M. de B. Cardiovascular responses in apnoeic asphyxia: role of arterial chemoreceptors and the modification of their effects by a pulmonary vagal inflation reflex. J Physiol. 1969 Mar;201(1):87–104. doi: 10.1113/jphysiol.1969.sp008744. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. James J. E., De Burgh Daly M. Reflex respiratory and cardiovascular effects of stimulation of receptors in the nose of the dog. J Physiol. 1972 Feb;220(3):673–696. doi: 10.1113/jphysiol.1972.sp009729. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. KEATINGE W. R., NADEL J. A. IMMEDIATE RESPIRATORY RESPONSE TO SUDDEN COOLING OF THE SKIN. J Appl Physiol. 1965 Jan;20:65–69. doi: 10.1152/jappl.1965.20.1.65. [DOI] [PubMed] [Google Scholar]
  12. Kawakami Y., Natelson B. H., DuBois A. R. Cardiovascular effects of face immersion and factors affecting diving reflex in man. J Appl Physiol. 1967 Dec;23(6):964–970. doi: 10.1152/jappl.1967.23.6.964. [DOI] [PubMed] [Google Scholar]
  13. Keatinge W. R., Sloan R. E. Deep body temperature from aural canal with servo-controlled heating to outer ear. J Appl Physiol. 1975 May;38(5):919–921. doi: 10.1152/jappl.1975.38.5.919. [DOI] [PubMed] [Google Scholar]
  14. Lum L. C. Hyperventilation and anxiety state. J R Soc Med. 1981 Jan;74(1):1–4. doi: 10.1177/014107688107400101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Moore T. O., Lin Y. C., Lally D. A., Hong S. K. Effects of temperature, immersion, and ambient pressure on human apneic bradycardia. J Appl Physiol. 1972 Jul;33(1):36–41. doi: 10.1152/jappl.1972.33.1.36. [DOI] [PubMed] [Google Scholar]
  16. Mukhtar M. R., Patrick J. M. Bronchoconstriction: a component of the 'diving response' in man. Eur J Appl Physiol Occup Physiol. 1984;53(2):155–158. doi: 10.1007/BF00422579. [DOI] [PubMed] [Google Scholar]
  17. Stromme S. B., Kerem D., Elsner R. Diving bradycardia during rest and exercise and its relation to physical fitness. J Appl Physiol. 1970 May;28(5):614–621. doi: 10.1152/jappl.1970.28.5.614. [DOI] [PubMed] [Google Scholar]
  18. Tchobroutsky C., Merlet C., Rey P. The diving reflex in rabbit, sheep and newborn lamb and its afferent pathways. Respir Physiol. 1969 Dec;8(1):108–117. doi: 10.1016/0034-5687(69)90048-6. [DOI] [PubMed] [Google Scholar]
  19. Verhaegen M. J. The Aquatic Ape Theory: evidence and a possible scenario. Med Hypotheses. 1985 Jan;16(1):17–32. doi: 10.1016/0306-9877(85)90036-2. [DOI] [PubMed] [Google Scholar]
  20. Whayne T. F., Jr, Killip T., 3rd Simulated diving in man: comparison of facial stimuli and response in arrhythmia. J Appl Physiol. 1967 Apr;22(4):800–807. doi: 10.1152/jappl.1967.22.4.800. [DOI] [PubMed] [Google Scholar]
  21. Wolf S., Schneider R. A., Groover M. E. Further studies on the circulatory and metabolic alterations of the oxygen-conserving (diving) reflex in man. Trans Assoc Am Physicians. 1965;78:242–254. [PubMed] [Google Scholar]

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