Abstract
The aetiology of genital ulceration was studied in 104 unselected patients (94 men, 10 women) attending a sexually transmitted disease (STD) clinic in the Gambia. Chancroid was diagnosed in 54 (52%), syphilis in 23 (22%), lymphogranuloma venereum (LGV) in seven (7%), and herpes in six (6%). In 28 (27%) patients no diagnosis was reached. Ten (10%) patients were found to have both chancroid and syphilis, three (3%) had both LGV and syphilis, and one (1%) had both herpes and syphilis. Trimethoprim 160 mg and sulphamethoxazole 800 mg twice daily for one week was found to be effective in the treatment of chancroid. This regimen with a single intramuscular injection of benzathine penicillin 2.4 MIU is recommended for the treatment of genital ulcers in Gambian health centres without laboratory facilities.
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Selected References
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- Chapel T. A., Brown W. J., Jeffres C., Stewart J. A. How reliable is the morphological diagnosis of penile ulcerations? Sex Transm Dis. 1977 Oct-Dec;4(4):150–152. doi: 10.1097/00007435-197710000-00008. [DOI] [PubMed] [Google Scholar]
- Chapel T., Brown W. J., Jeffries C., Stewart J. A. The microbiological flora of penile ulcerations. J Infect Dis. 1978 Jan;137(1):50–56. doi: 10.1093/infdis/137.1.50. [DOI] [PubMed] [Google Scholar]
- Fast M. V., D'Costa L. J., Nsanze H., Piot P., Curran J., Karasira P., Mirza N., Maclean I. W., Ronald A. R. The clinical diagnosis of genital ulcer disease in men in the tropics. Sex Transm Dis. 1984 Apr-Jun;11(2):72–76. doi: 10.1097/00007435-198404000-00004. [DOI] [PubMed] [Google Scholar]
- Forsey T., Darougar S. Indirect micro-immunofluorescence test for detecting type-specific antibodies to herpes simplex virus. J Clin Pathol. 1980 Feb;33(2):171–176. doi: 10.1136/jcp.33.2.171. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Joshi R. M., Lawande R. V. Chancroid in Nigeria. Trans R Soc Trop Med Hyg. 1983;77(5):665–667. doi: 10.1016/0035-9203(83)90198-0. [DOI] [PubMed] [Google Scholar]
- Kinghorn G. R., Hafiz S., McEntegart M. G. Pathogenic microbial flora of genital ulcers in Sheffield with particular reference to herpes simplex virus and Haemophilus ducreyi. Br J Vener Dis. 1982 Dec;58(6):377–380. doi: 10.1136/sti.58.6.377. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mabey D. C., Lloyd-Evans N. E., Conteh S., Forsey T. Sexually transmitted diseases among randomly selected attenders at an antenatal clinic in The Gambia. Br J Vener Dis. 1984 Oct;60(5):331–336. doi: 10.1136/sti.60.5.331. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Meheus A., Van Dyck E., Friedman F. Genital infections in Swaziland. Ann Soc Belg Med Trop. 1982 Dec;62(4):361–367. [PubMed] [Google Scholar]
- Meheus A., Van Dyck E., Ursi J. P., Ballard R. C., Piot P. Etiology of genital ulcerations in Swaziland. Sex Transm Dis. 1983 Jan-Mar;10(1):33–35. doi: 10.1097/00007435-198301000-00007. [DOI] [PubMed] [Google Scholar]
- Nsanze H., Fast M. V., D'Costa L. J., Tukei P., Curran J., Ronald A. Genital ulcers in Kenya. Clinical and laboratory study. Br J Vener Dis. 1981 Dec;57(6):378–381. doi: 10.1136/sti.57.6.378. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sogbetun A. O., Montefiore D., Anong C. N. Herpesvirus hominis antibodies among children and young adults in Ibadan. Br J Vener Dis. 1979 Feb;55(1):44–47. doi: 10.1136/sti.55.1.44. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sottnek F. O., Biddle J. W., Kraus S. J., Weaver R. E., Stewart J. A. Isolation and identification of Haemophilus ducreyi in a clinical study. J Clin Microbiol. 1980 Aug;12(2):170–174. doi: 10.1128/jcm.12.2.170-174.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]