Skip to main content
NCBI home page
Genitourinary Medicine logoLink to Genitourinary Medicine
. 1991 Aug;67(4):291–296. doi: 10.1136/sti.67.4.291

Genital human papillomavirus lesions of the male sexual partners: the diagnostic accuracy of peniscopy.

M Hippeläinen 1, M Yliskoski 1, S Saarikoski 1, S Syrjänen 1, K Syrjänen 1
PMCID: PMC1194703  PMID: 1655625

Abstract

OBJECTIVES--To evaluate the accuracy of peniscopy for identifying human papillomavirus (HPV) lesions in male sexual partners of women with HPV infection. The predictive value of the medical history for HPV infection was also evaluated. DESIGN--Examination of voluntary male partners of the women with HPV infection using colposcopy (peniscopy after acetic acid), cytology and surgical biopsy, the latter being analysed by light microscopy, in situ hybridisation (ISH) and polymerase chain reaction (PCR) for HPV DNA. A detailed medical history was to be taken, too. SETTING--Department of Gynaecology and Obstetrics, Kuopio University Central Hospital, Finland. SUBJECTS--A series of 101 voluntary male partners of 101 women invited for examination, treatment and follow-up for their genital HPV infections on the basis of abnormal Papanicolaou (PAP) smears. RESULTS--On peniscopy 64 (63.4%) of the men presented with lesions either typical of (34.7%) or suspicious for (28.7%) HPV infection. Of the latter, 89% were flat lesions mostly undetectable by the naked eye. The cytologic smear was positive in only nine men. On light microscope, 85.7% of the peniscopically typical lesions were found to be consistent with (68.6%) or suspicious for (17.1%) HPV infection. HPV DNA was found in 33 (34.5%) of the 96 typed biopsies, and never in biopsies from peniscopically healthy areas. In logistic regression analysis of the historical data recorded, only the contact time with the current sexual partner was of predictive value for histologically proven HPV infection. CONCLUSIONS--Peniscopy is an applicable means for the identification of penile lesions due to HPV infection, but it is not a conclusive diagnostic tool capable of differentiating HPV from non-HPV findings.

Full text

PDF
291

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baggish M. S. Treating viral venereal infections with the CO2 laser. J Reprod Med. 1982 Dec;27(12):737–742. [PubMed] [Google Scholar]
  2. Barrasso R., De Brux J., Croissant O., Orth G. High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia. N Engl J Med. 1987 Oct 8;317(15):916–923. doi: 10.1056/NEJM198710083171502. [DOI] [PubMed] [Google Scholar]
  3. Bistoletti P., Lidbrink P. Sexually transmitted diseases including genital papillomavirus infection in male sexual partners of women treated for cervical intraepithelial neoplasia III by conization. Br J Obstet Gynaecol. 1988 Jun;95(6):611–613. doi: 10.1111/j.1471-0528.1988.tb09493.x. [DOI] [PubMed] [Google Scholar]
  4. Campion M. J., McCance D. J., Mitchell H. S., Jenkins D., Singer A., Oriel J. D. Subclinical penile human papillomavirus infection and dysplasia in consorts of women with cervical neoplasia. Genitourin Med. 1988 Apr;64(2):90–99. doi: 10.1136/sti.64.2.90. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Campion M. J., Singer A., Clarkson P. K., McCance D. J. Increased risk of cervical neoplasia in consorts of men with penile condylomata acuminata. Lancet. 1985 Apr 27;1(8435):943–946. doi: 10.1016/s0140-6736(85)91724-6. [DOI] [PubMed] [Google Scholar]
  6. Ferenczy A., Mitao M., Nagai N., Silverstein S. J., Crum C. P. Latent papillomavirus and recurring genital warts. N Engl J Med. 1985 Sep 26;313(13):784–788. doi: 10.1056/NEJM198509263131304. [DOI] [PubMed] [Google Scholar]
  7. Kennedy L., Buntine D. W., O'Connor D., Frazer I. H. Human papillomavirus--a study of male sexual partners. Med J Aust. 1988 Sep 19;149(6):309–311. doi: 10.5694/j.1326-5377.1988.tb120630.x. [DOI] [PubMed] [Google Scholar]
  8. Krebs H. B. Genital HPV infections in men. Clin Obstet Gynecol. 1989 Mar;32(1):180–190. doi: 10.1097/00003081-198903000-00022. [DOI] [PubMed] [Google Scholar]
  9. Krebs H. B., Schneider V. Human papillomavirus-associated lesions of the penis: colposcopy, cytology, and histology. Obstet Gynecol. 1987 Sep;70(3 Pt 1):299–304. [PubMed] [Google Scholar]
  10. Levine R. U., Crum C. P., Herman E., Silvers D., Ferenczy A., Richart R. M. Cervical papillomavirus infection and intraepithelial neoplasia: a study of male sexual partners. Obstet Gynecol. 1984 Jul;64(1):16–20. [PubMed] [Google Scholar]
  11. Nash J. D., Burke T. W., Hoskins W. J. Biologic course of cervical human papillomavirus infection. Obstet Gynecol. 1987 Feb;69(2):160–162. [PubMed] [Google Scholar]
  12. Rosemberg S. K., Reid R. Sexually transmitted papillomaviral infections in the male: I. Anatomic distribution and clinical features. Urology. 1987 May;29(5):488–492. doi: 10.1016/0090-4295(87)90034-3. [DOI] [PubMed] [Google Scholar]
  13. Sand P. K., Bowen L. W., Blischke S. O., Ostergard D. R. Evaluation of male consorts of women with genital human papilloma virus infection. Obstet Gynecol. 1986 Nov;68(5):679–681. [PubMed] [Google Scholar]
  14. Sedlacek T. V., Cunnane M., Carpiniello V. Colposcopy in the diagnosis of penile condyloma. Am J Obstet Gynecol. 1986 Mar;154(3):494–496. doi: 10.1016/0002-9378(86)90589-2. [DOI] [PubMed] [Google Scholar]
  15. Stone K. M. Epidemiologic aspects of genital HPV infection. Clin Obstet Gynecol. 1989 Mar;32(1):112–116. doi: 10.1097/00003081-198903000-00016. [DOI] [PubMed] [Google Scholar]
  16. Syrjänen S., Saastamoinen J., Chang F. J., Ji H. X., Syrjänen K. Colposcopy, punch biopsy, in situ DNA hybridization, and the polymerase chain reaction in searching for genital human papillomavirus (HPV) infections in women with normal PAP smears. J Med Virol. 1990 Aug;31(4):259–266. doi: 10.1002/jmv.1890310404. [DOI] [PubMed] [Google Scholar]
  17. Yliskoski M., Saarikoski S., Syrjänen K., Syrjänen S., Castrén O. Cryotherapy and CO2-laser vaporization in the treatment of cervical and vaginal human papillomavirus (HPV) infections. Acta Obstet Gynecol Scand. 1989;68(7):619–625. doi: 10.3109/00016348909013281. [DOI] [PubMed] [Google Scholar]

Articles from Genitourinary Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES