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. 2025 Mar 14;16:1524452. doi: 10.3389/fmicb.2025.1524452

Table 2.

Meta-analysis statistics of worldwide antibiotic resistance in Staphylococcus spp.

Antibiotic K (n, N) Proportion 95%CI (LCI, HCI) I2 P1 P2
Erythromycin 721 (144,746, 293,411) 0.573 (0.556, 0.590) 98.29% p < 0.001 p < 0.001
Clarithromycin 30 (4,015, 8,045) 0.526 (0.380, 0.668) 98.76% p = 0.727 p < 0.001
Azithromycin 83 (5,227, 10,553) 0.579 (0.514, 0.641) 96.50% p = 0.017 p < 0.001

K: Number of reports, n: Number of resistant isolates, N: Number of total isolates, LCI: 95% Lower Limit Confidence Interval, HCI: 95% Higher Limit Confidence Interval, P1: p-value of difference from zero resistance rate, P2: p-value of heterogeneity between reports.