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. 1959 Apr;71(4):680–690. doi: 10.1042/bj0710680

The formation of mercapturic acids. 1. Formation of mercapturic acid and the levels of glutathione in tissues

M M Barnes 1, Sybil P James 1, P B Wood 1
PMCID: PMC1196858  PMID: 13651117

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSON E. I., MOSHER W. A. Incorporation of S35 from DL-cystine into glutathione and protein in the rat. J Biol Chem. 1951 Feb;188(2):717–722. [PubMed] [Google Scholar]
  2. BETTS J. J., JAMES S. P., THORPE W. V. The metabolism of pentachloronitrobenzene and 2:3:4:6-tetrachloronitrobenzene and the formation of mercapturic acids in the rabbit. Biochem J. 1955 Dec;61(4):611–617. doi: 10.1042/bj0610611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BHATTACHARYA S. K., ROBSON J. S., STEWART C. P. The determination of glutathione in blood and tissues. Biochem J. 1955 Aug;60(4):696–702. doi: 10.1042/bj0600696. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BINET L., WELLERS G. Rôle du glutathion lors de l'intoxication du rat par le monobromobenzène. Bull Soc Chim Biol (Paris) 1951;33(3-4):279–285. [PubMed] [Google Scholar]
  5. BOYLAND E., SIMS P. Metabolism of polycyclic compounds. 12. An acid-labile precursor of 1-naphthylmercapturic acid and naphthol: an N-acetyl-S-(1:2-dihydrohydroxy-naphthyl)-L-cysteine. Biochem J. 1958 Mar;68(3):440–447. doi: 10.1042/bj0680440. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. BRAY H. G., FRANKLIN T. J., JAMES S. P. The formation of mercapturic acids. 2. The possible role of glutathionase. Biochem J. 1959 Apr;71(4):690–696. doi: 10.1042/bj0710690. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. BRAY H. G., HYBS Z., JAMES S. P., THORPE W. V. The metabolism of 2:3:5:6- and 2:3:4:5-tetrachloronitrobenzenes in the rabbit and the reduction of aromatic nitro compounds in the intestine. Biochem J. 1953 Jan;53(2):266–273. doi: 10.1042/bj0530266. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. BRAY H. G., JAMES S. P., THORPE W. V. Metabolism of o-, m- and p-fluoro-, bromo- and -iodo-nitrobenzenes in the rabbit. Biochem J. 1958 Apr;68(4):561–568. doi: 10.1042/bj0680561b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. BRAY H. G., JAMES S. P., THORPE W. V. Metabolism of some omega-halogenoalkylbenzenes and related alcohols in the rabbit. Biochem J. 1958 Dec;70(4):570–579. doi: 10.1042/bj0700570. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. BRAY H. G., JAMES S. P., THORPE W. V. The metabolism of 2:4-,2:5-and 3:4-dichloronitrobenzene in the rabbit. Biochem J. 1957 Mar;65(3):483–490. doi: 10.1042/bj0650483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. BRAY H. G., JAMES S. P., THORPE W. V. The metabolism of the monochloronitrobenzenes in the rabbit. Biochem J. 1956 Sep;64(1):38–44. doi: 10.1042/bj0640038. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. BRAY H. G., THORPE W. V., VALLANCE D. K. The liberation of chloride ions from organic chloro compounds by tissue extracts. Biochem J. 1952 May;51(2):193–201. [PMC free article] [PubMed] [Google Scholar]
  13. BRAY H. G., THORPE W. V., WHITE K. Kinetic studies of the metabolism of foreign organic compounds; the formation of benzoic acid from benzamide toluene, benzyl alcohol and benzaldehyde and its conjugation with glycine and glucuronic acid in the rabbit. Biochem J. 1951 Jan;48(1):88–96. doi: 10.1042/bj0480088. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Bourne M. C., Young L. The metabolism of naphthalene in rabbits. Biochem J. 1934;28(3):803–808. doi: 10.1042/bj0280803. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. GUTMANN H. R., WOOD J. L. The effect of bromobenzene and 3,4-benzpyrene on the metabolism of radioactive L-cystine. Cancer Res. 1950 Jan;10(1):8–12. [PubMed] [Google Scholar]
  16. HENRIQUES O. B., HENRIQUES S. B., NEUBERGER A. Quantitative aspects of glycine metabolism in the rabbit. Biochem J. 1955 Jul;60(3):409–424. doi: 10.1042/bj0600409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. HEYWORTH R., BACON J. S. A nitrogenous derivative of lactose from lactating rat mammary gland. Biochem J. 1957 May;66(1):41–47. [PMC free article] [PubMed] [Google Scholar]
  18. KELLOGG R. H., BURACK W. R., ISSELBACHER K. J. Comparison of diuresis produced by isotonic saline solutions and by water in rats studied by a steady state method. Am J Physiol. 1954 Apr;177(1):27–37. doi: 10.1152/ajplegacy.1954.177.1.27. [DOI] [PubMed] [Google Scholar]
  19. KNIGHT R. H., YOUNG L. Biochemical studies of toxic agents. 11. The occurrence of premercapturic acids. Biochem J. 1958 Sep;70(1):111–119. doi: 10.1042/bj0700111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. MARSDEN C. M., YOUNG L. Biochemical studies of toxic agents. 10. Observations on the metabolism of 35S-labelled mercapturic acids. Biochem J. 1958 Jun;69(2):257–265. doi: 10.1042/bj0690257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. MARTIN H., McILWAIN H. Glutathione, oxidized and reduced, in the brain and in isolated cerebral tissue. Biochem J. 1959 Feb;71(2):275–280. doi: 10.1042/bj0710275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. MILLS G. C., WOOD J. L. Mercapturic acid precursors. J Biol Chem. 1956 Mar;219(1):1–8. [PubMed] [Google Scholar]
  23. ROBERTS J. J., WARWICK G. P. Mode of action of alkylating agents: formation of S-ethylcysteine from ethyl methanesulphonate in vivo. Nature. 1957 Jun 8;179(4571):1181–1182. doi: 10.1038/1791181a0. [DOI] [PubMed] [Google Scholar]
  24. SIMKIN J. L., WHITE K. The formation of hippuric acid; the influence of benzoate administration on tissue glycine levels. Biochem J. 1957 Mar;65(3):574–582. doi: 10.1042/bj0650574. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. SNYDER F., CORNATZER W. E. Sulfur metabolism in chemically induced necrotic liver degeneration. J Biol Chem. 1958 Apr;231(2):839–847. [PubMed] [Google Scholar]
  26. SPENCER B., WILLIAMS R. T. Studies in detoxication; the metabolism of halogenobenzenes. A comparison of the glucuronic acid, ethereal sulphate and mercapturic acid conjugations of chloro-, bromo- and iodo-benzenes and of the o-, m- and p-chlorophenols. Biosynthesis of o-, m- and p-chlorophenylglucuronides. Biochem J. 1950 Sep;47(3):279–284. doi: 10.1042/bj0470279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. SPENCER B., WILLIAMS R. T. Studies in detoxication; the metabolism of halogenobenzenes. A comparison of the glucuronic acid, ethereal sulphate and mercapturic acid conjugations of chloro-, bromo- and iodo-benzenes and of the o-, m- and p-chlorophenols. Biosynthesis of o-, m- and p-chlorophenylglucuronides. Biochem J. 1950 Sep;47(3):279–284. doi: 10.1042/bj0470279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. WAELSCH H. Certain aspects of intermediary metabolism of glutamine, asparagine, and glutathione. Adv Enzymol Relat Subj Biochem. 1952;13:237–319. doi: 10.1002/9780470122587.ch7. [DOI] [PubMed] [Google Scholar]
  29. WEST H. D., MATHURA G. R., BLACK L. A. Laboratory synthesis of p-chlorophenyl-L-cysteine and its acetylation by the rat. J Biol Chem. 1951 Nov;193(1):133–135. [PubMed] [Google Scholar]
  30. WEST H. D., MATHURA G. R. Synthesis of some aryl-substituted L-cysteines and their fate in the animal body. J Biol Chem. 1954 May;208(1):315–318. [PubMed] [Google Scholar]

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