Skip to main content
PMC home page
Biochemical Journal logoLink to Biochemical Journal
. 1951 Oct;49(5):686–693. doi: 10.1042/bj0490686

The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid

W E Knox 1, M LeMay-Knox 1
PMCID: PMC1197578  PMID: 14886367

Full text

PDF
686

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bray H. G., Thorpe W. V., White K. The fate of certain organic acids and amides in the rabbit. 10. The application of paper chromatography to metabolic studies of hydroxybenzoic acids and amides. Biochem J. 1950 Mar;46(3):271–275. doi: 10.1042/bj0460271. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CAMMARATA P. S., COHEN P. P. The scope of the transamination reaction in animal tissues. J Biol Chem. 1950 Nov;187(1):439–452. [PubMed] [Google Scholar]
  3. Demole V. On the physiological action of ascorbic acid and some related compounds. Biochem J. 1934;28(3):770–773. doi: 10.1042/bj0280770. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Edson N. L. Ketogenesis-antiketogenesis: Ketogenesis from amino-acids. Biochem J. 1935 Nov;29(11):2498–2505. doi: 10.1042/bj0292498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Edson N. L. Ketogenesis-antiketogenesis: The influence of ammonium chloride on ketone-body formation in liver. Biochem J. 1935 Sep;29(9):2082–2094. doi: 10.1042/bj0292082. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FELDMAN L. I., GUNSALUS I. C. The occurrence of a wide variety of transaminases in bacteria. J Biol Chem. 1950 Dec;187(2):821–830. [PubMed] [Google Scholar]
  7. GILBERT G. A., SWALLOW A. J. Studies in dialysis; changes of pH during dialysis. Biochem J. 1950 Oct;47(4):506–508. doi: 10.1042/bj0470506. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Gale E. F. Studies on bacterial amino-acid decarboxylases: 5. The use of specific decarboxylase preparations in the estimation of amino-acids and in protein analysis. Biochem J. 1945;39(1):46–52. doi: 10.1042/bj0390046. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. HIRD F. J. R., ROWSELL E. V. Additional transaminations by insoluble particle preparations of rat liver. Nature. 1950 Sep 23;166(4221):517–518. doi: 10.1038/166517a0. [DOI] [PubMed] [Google Scholar]
  10. KNOX W. E., MEHLER A. H. The conversion of tryptophan to kynurenine in liver. I. The coupled tryptophan peroxidase-oxidase system forming formylkynurenine. J Biol Chem. 1950 Nov;187(1):419–430. [PubMed] [Google Scholar]
  11. LE MAY-KNOX M., KNOX W. E. The transamination and oxidation of L-tyrosine by rat liver with the formation of acetoacetate. Biochem J. 1951 Feb;48(2):xxii–xxiii. [PubMed] [Google Scholar]
  12. LERNER A. B. On the metabolism of phenylalanine and tyrosine. J Biol Chem. 1949 Nov;181(1):281–294. [PubMed] [Google Scholar]
  13. Levine S. Z., Marples E., Gordon H. H. A DEFECT IN THE METABOLISM OF TYROSINE AND PHENYLALANINE IN PREMATURE INFANTS. I. IDENTIFICATION AND ASSAY OF INTERMEDIARY PRODUCTS. J Clin Invest. 1941 Mar;20(2):199–207. doi: 10.1172/JCI101212. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Medes G. A new error of tyrosine metabolism: tyrosinosis. The intermediary metabolism of tyrosine and phenylalanine. Biochem J. 1932;26(4):917–940. doi: 10.1042/bj0260917. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Neuberger A., Rimington C., Wilson J. M. Studies on alcaptonuria: 2. Investigations on a case of human alcaptonuria. Biochem J. 1947;41(3):438–449. [PMC free article] [PubMed] [Google Scholar]
  16. Neuberger A. Studies on alcaptonuria: 1. The estimation of homogentisic acid. Biochem J. 1947;41(3):431–438. doi: 10.1042/bj0410431. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. PAINTER H. A., ZILVA S. S. The influence of L-ascorbic acid on the disappearance of the phenolic group of L-tyrosine in the presence of guinea pig-liver suspensions. Biochem J. 1950 May;46(5):542–546. doi: 10.1042/bj0460542. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Painter H. A., Zilva S. S. The influence of l-ascorbic acid on the rupture of the benzene ring of l-tyrosine consumed in high doses by guinea-pigs. Biochem J. 1947;41(4):511–519. [PMC free article] [PubMed] [Google Scholar]
  19. Zilva S. S. The behaviour of l-ascorbic acid and chemically related compounds in the animal body. Antiscorbutic activity in relation to retention by the organism. Biochem J. 1935 Jul;29(7):1612–1616. doi: 10.1042/bj0291612. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES