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. 1967 Dec;105(3):995–1002. doi: 10.1042/bj1050995

Lactogenesis in the rat. Changes in metabolic parameters at parturition

N J Kuhn 1,*, J M Lowenstein 1
PMCID: PMC1198418  PMID: 16742576

Abstract

1. Tissue concentrations of nucleic acids, protein, fat, water, metabolites and lactose, and the activities of seven enzymes concerned in milk biosynthesis, were measured in the rat mammary gland at closely spaced times before, at and after parturition. 2. Changes are seen in the tissue concentrations of most substances, and several changes are initiated at least during the day preceding parturition. 3. Lactose, which is absent 1 day before parturition, is found in amounts of 12μmoles/g. fresh wt. of tissue at parturition. 4. From the tissue activities before parturition of three enzymes on the biosynthetic pathway of lactose, and, from the small changes observed in their activities at parturition itself, it is concluded that the factors responsible for the appearance of lactose at parturition remain to be demonstrated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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