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. 1968 Feb;106(3):743–748. doi: 10.1042/bj1060743

Lactogenesis in the rat. Metabolism of uridine diphosphate galactose by mammary gland

N J Kuhn 1,*
PMCID: PMC1198567  PMID: 5639929

Abstract

1. Lactose synthetase activity in the rat mammary gland increases during the last day of pregnancy from an essentially zero value. There is a parallel increase of tissue lactose and of glucose 6-phosphate dehydrogenase activity. 2. Mammary-gland homogenates prepared both before and after parturition hydrolyse the lactose precursors glucose 6-phosphate, glucose 1-phosphate, UDP-glucose, UDP-galactose and also maltose, but not lactose. 3. A role of lactose synthetase as the rate-limiting enzyme for lactose biosynthesis and the possible significance of the hydrolytic activities are discussed with respect to lactogenesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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