Skip to main content
Internal Medicine logoLink to Internal Medicine
. 2024 Aug 10;64(6):981–982. doi: 10.2169/internalmedicine.4168-24

The Predominance of the Upper Lung Fields in Pulmonary Tuberculosis

Jiro Fujita 1, Tetsu Chinen 1, Kazutaka Yamaniha 1, Motoo Baba 1
PMCID: PMC11986320  PMID: 39135247

The upper lung lobes and segment 6 are affected in secondary tuberculosis as an endogenous reactivation of past infection that can be explained by a higher degree of oxygen tension and a lower blood flow, i.e., a higher ventilation/perfusion (V/Q) ratio than the base lung fields (1).

A 65-year-old male with no underlying disease presented to our emergency department with a cough, fever, and weight loss. Chest computed tomography (CT) showed thin, bilateral cavitary lesions with an upper lung field predominance (Picture A, B). Mycobacterium tuberculosis was detected in the sputum samples.

Picture.

Picture.

Rothlin et al. analyzed the pathological findings of secondary tuberculosis in various animals (2). In pattern diagrams included in the paper (Picture C, D, E, F, and G), it is clearly shown that the distribution of the lesions of secondary tuberculosis is affected by the body position in which various animals live (2). Clinicians should therefore consider the distribution of pulmonary tuberculosis lesions for such cases (1,2).

The authors state that they have no Conflict of Interest (COI).

References

  • 1.Goto A, Komiya K, Kan T, et al. Factors associated with atypical radiological findings of pulmonary tuberculosis. PLoS One 14: e0220346, 2019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Rothlin E, Undritz E. Beitrag zur Lokalisationsregel der Tuberkulose. Schweiz Z Pathol Bakteriol 15: 690-700, 1952. (in German). [PubMed] [Google Scholar]

Articles from Internal Medicine are provided here courtesy of Japanese Society of Internal Medicine

RESOURCES