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. 1968 Jun;108(1):95–99. doi: 10.1042/bj1080095

The distribution of monoamine oxidase and α-glycerophosphate dehydrogenase in pig brain

K F Tipton 1, A P Dawson 1,*
PMCID: PMC1198773  PMID: 4297941

Abstract

Activities of the enzymes monoamine oxidase (EC 1.4.3.4), α-glycerophosphate dehydrogenase (EC 1.1.99.5) and cytochrome oxidase (EC 1.9.3.1) were determined in homogenates and in the mitochondrial fraction prepared from individual regions of pig brain. The variation in the activity of α-glycerophosphate dehydrogenase paralleled that of cytochrome oxidase, but this was not the case with monoamine oxidase. The differences in the activities of the enzymes among homogenates of the various regions of the brain persisted in mitochondria prepared from these homogenates. The purification of these three enzymes paralleled each other when mitochondria were prepared, suggesting that the three enzymes are bound to the same particles.

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Selected References

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