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. 1968 Jul;108(3):369–373. doi: 10.1042/bj1080369

Interaction of polypeptide hormones with lipid momolayers

R S Snart 1, N N Sanyal 1
PMCID: PMC1198821  PMID: 4299125

Abstract

1. The interaction between lipid monolayers spread on the surface of water and oxytocin, [8-arginine]-vasotocin and [1-asparagine-5-valine]-angiotensin II in the subphase was investigated in a Langmuir surface trough by studying the changes in pressure produced on injection of various quantities of the polypeptide solution under the film. 2. The effect of 2m- and 4m-urea on the character of the adsorption is reported. 3. Structures for the adsorbed films formed in this way are suggested. 4. If the lipid monolayer is taken as a suitable model of cell membranes, then it may be supposed that the effect of such structures forming in cell membranes would be to provide effective `pores' to facilitate the movement of water and other small molecules across the membrane.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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