Abstract
Complementation tests among previously isolated rex- mutants of bacteriophage λ reveal that the mutants comprise two complementation groups, designated rexA and rexB. Because rexB- mutants complement prm- mutants, but rexA- mutants do not, it appears that the rexA gene is coordinately controlled with the cI (repressor) gene under the direction of the PRM promoter, but that some other promoter is capable of directing the expression of rexB.
Full Text
The Full Text of this article is available as a PDF (556.8 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Astrachan L., Miller J. F. Regulation of lambda rex expression after infection of Escherichia coli K by lambda bacteriophage. J Virol. 1972 Mar;9(3):510–518. doi: 10.1128/jvi.9.3.510-518.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gussin G. N., Peterson V., Loeb N. Deletion mapping of the lambda REX gene. Genetics. 1973 Jul;74(3):385–392. doi: 10.1093/genetics/74.3.385. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KAISER A. D., JACOB F. Recombination between related temperate bacteriophages and the genetic control of immunity and prophage localization. Virology. 1957 Dec;4(3):509–521. doi: 10.1016/0042-6822(57)90083-1. [DOI] [PubMed] [Google Scholar]
- Lieb M., Talland C. IS elements in bacteriophage lambda gene cI prevent expression of gene rex. J Virol. 1981 May;38(2):789–791. doi: 10.1128/jvi.38.2.789-791.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pao C. C., Speyer J. F. Mutants of T7 bacteriophage inhibited by lambda prophage. Proc Natl Acad Sci U S A. 1975 Sep;72(9):3642–3646. doi: 10.1073/pnas.72.9.3642. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pirrotta V., Ineichen K., Walz A. An unusual RNA polymerase binding site in the immunity region of phage lambda. Mol Gen Genet. 1980;180(2):369–376. doi: 10.1007/BF00425850. [DOI] [PubMed] [Google Scholar]
- Siebenlist U., Simpson R. B., Gilbert W. E. coli RNA polymerase interacts homologously with two different promoters. Cell. 1980 Jun;20(2):269–281. doi: 10.1016/0092-8674(80)90613-3. [DOI] [PubMed] [Google Scholar]
- Susskind M. M., Botstein D. Superinfection exclusion by lambda prophage in lysogens of Salmonella typhimurium. Virology. 1980 Jan 15;100(1):212–216. doi: 10.1016/0042-6822(80)90571-1. [DOI] [PubMed] [Google Scholar]
- Toothman P., Herskowitz I. Rex-dependent exclusion of lambdoid phages. I. Prophage requirements for exclusion. Virology. 1980 Apr 15;102(1):133–146. doi: 10.1016/0042-6822(80)90076-8. [DOI] [PubMed] [Google Scholar]
- Yen K. M., Gussin G. N. Genetic characterization of a prm- mutant of bacteriophage lambda. Virology. 1973 Nov;56(1):300–312. doi: 10.1016/0042-6822(73)90308-5. [DOI] [PubMed] [Google Scholar]