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. 1983 May;104(1):1–9. doi: 10.1093/genetics/104.1.1

Involvement of Gene 49 in Recombination of Bacteriophage T4

Junichi Miyazaki 1, Yeikou Ryo 1, Teiichi Minagawa 1
PMCID: PMC1202056  PMID: 6345264

Abstract

The role of T4 gene 49 in recombination was investigated using its conditional-lethal amber (am) and temperature-sensitive (ts) mutants. When measured in genetic tests, defects in gene 49 produced a recombination-deficient phenotype. However, DNA synthesized in cells infected with a ts mutant (tsC9) at a nonpermissive temperature appeared to be in a recombinogenic state: after restitution of gene function by shifting to a permissive temperature, the recombinant frequency among progeny increased rapidly even when DNA replication was blocked by an inhibitor. Growth of a gene 49-defective mutant was suppressed by an additional mutation in gene uvsX, but recombination between rII markers was not.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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