Abstract
The amount and form of natural genetic variation for recombination were studied in six lines for which second chromosomes were extracted from a natural population of Drosophila melanogaster. Multiply marked second, X and third chromosomes were used to score recombination. Recombination in the second chromosomes varied in both amount and distribution. These second chromosomes caused variation in the amount and distribution of crossing over in the X chromosome and also caused variation in the amount, but not the distribution, of crossing over in the third chromosome. The total amount of crossing over on a chromosome varied by 12–14%. One small region varied twofold; other regions varied by 16–38%. Lines with less crossing over on one chromosome generally had less crossing over on other chromosomes, the opposite of the standard interchromosomal effect. These results show that modifiers of recombination can affect more than one chromosome, and that the variation exists for fine-scale response to selection on recombination.
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Selected References
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- Chinnici J. P. Modification of recombination frequency in Drosophila. I. Selection for increased and decreased crossing over. Genetics. 1971 Sep;69(1):71–83. doi: 10.1093/genetics/69.1.71. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Craig-Holmes A. P., Moore F. B., Shaw M. W. Polymorphism of human C-band heterochromatin. I. Frequency of variants. Am J Hum Genet. 1973 Mar;25(2):181–192. [PMC free article] [PubMed] [Google Scholar]
- Ebinuma H., Yoshitake N. The genetic system controlling recombination in the silkworm. Genetics. 1981 Oct;99(2):231–245. doi: 10.1093/genetics/99.2.231. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Eshel I., Feldman M. W. On the evolutionary effect of recombination. Theor Popul Biol. 1970 May;1(1):88–100. doi: 10.1016/0040-5809(70)90043-2. [DOI] [PubMed] [Google Scholar]
- Feldman M. W., Christiansen F. B., Brooks L. D. Evolution of recombination in a constant environment. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4838–4841. doi: 10.1073/pnas.77.8.4838. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Levine R P, Levine E E. The Genotypic Control of Crossing over in Drosophila Pseudoobscura. Genetics. 1954 Sep;39(5):677–691. doi: 10.1093/genetics/39.5.677. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Levine R P, Levine E E. Variable Crossing over Arising in Different Strains of Drosophila Pseudoobscura. Genetics. 1955 May;40(3):399–405. doi: 10.1093/genetics/40.3.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lindsley D. L., Sandler L. The genetic analysis of meiosis in female Drosophila melanogaster. Philos Trans R Soc Lond B Biol Sci. 1977 Mar 21;277(955):295–312. doi: 10.1098/rstb.1977.0019. [DOI] [PubMed] [Google Scholar]
- MULLER H. J. THE RELATION OF RECOMBINATION TO MUTATIONAL ADVANCE. Mutat Res. 1964 May;106:2–9. doi: 10.1016/0027-5107(64)90047-8. [DOI] [PubMed] [Google Scholar]
- Miklos G. L., Nankivell R. N. Telomeric satellite DNA functions in regulating recombination. Chromosoma. 1976 Jun 30;56(2):143–167. doi: 10.1007/BF00293113. [DOI] [PubMed] [Google Scholar]
- Raper J. R., Baxter M. G., Ellingboe A. H. THE GENETIC STRUCTURE OF THE INCOMPATIBILITY FACTORS OF SCHIZOPHYLLUM COMMUNE: THE A-FACTOR. Proc Natl Acad Sci U S A. 1960 Jun;46(6):833–842. doi: 10.1073/pnas.46.6.833. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Slatko B. E., Hiraizumi Y. Elements causing male crossing over in Drosophila melanogaster. Genetics. 1975 Oct;81(2):313–324. doi: 10.1093/genetics/81.2.313. [DOI] [PMC free article] [PubMed] [Google Scholar]