Skip to main content
Genetics logoLink to Genetics
. 1987 Feb;115(2):363–366. doi: 10.1093/genetics/115.2.363

Use of the Multinomial Dirichlet Model for Analysis of Subdivided Genetic Populations

C J Jiang 1, C Clark Cockerham 1
PMCID: PMC1203085  PMID: 3557115

Abstract

The distribution found by compounding the multinomial distribution with the Dirichlet distribution has been suggested as a basis for the estimation of parameters in subdivided populations, in particular of the "correlation between genotypes" within subpopulations. It is shown that the estimators deriving from these procedures perform poorly when the data are generated by the classical Wright drift model of subdivided populations. This conclusion suggests that the compound distribution estimation approach does not provide a good estimation procedure for real populations which are reasonably described by the Wright model.

Full Text

The Full Text of this article is available as a PDF (321.2 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Rothman E. D., Sing C. F., Templeton A. R. A model for analysis of population structure. Genetics. 1974 Nov;78(3):943–960. doi: 10.1093/genetics/78.3.943. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. WRIGHT G. W. RESEARCH IN EMPHYSEMA. SUMMARY OF THE CONFERENCE. Med Thorac. 1965;22:420–431. doi: 10.1159/000192451. [DOI] [PubMed] [Google Scholar]

Articles from Genetics are provided here courtesy of Oxford University Press

RESOURCES