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. 1987 May;116(1):67–73. doi: 10.1093/genetics/116.1.67

Sequence of the Structural Gene for Xanthine Dehydrogenase ( rosy Locus) in Drosophila melanogaster

Tim P Keith 1,2, Margaret A Riley 1,2, Martin Kreitman 1,2, R C Lewontin 1,2, Daniel Curtis 1,2, Geoffrey Chambers 1,2
PMCID: PMC1203122  PMID: 3036646

Abstract

We determined the nucleotide sequence of a 4.6-kb EcoRI fragment containing 70% of the rosy locus. In combination with information on the 5' sequence, the gene has been sequenced in entirety. rosy cDNAs have been isolated and intron/exon boundaries have been determined. We find an open reading frame which spans four exons and would encode a protein of 1335 amino acids. The molecular weight of the encoded protein (xanthine dehydrogenase), based on the amino acid translation, is 146,898 daltons which agrees well with earlier biophysical estimates. Characteristics of the protein are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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