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. 1988 Oct;120(2):605–613. doi: 10.1093/genetics/120.2.605

The Maintenance of Single-Locus Polymorphism. I. Numerical Studies of a Viability Selection Model

H G Spencer 1, R W Marks 1
PMCID: PMC1203537  PMID: 3197961

Abstract

The ability of viability selection to maintain single-locus polymorphism is investigated with two models in which the population is bombarded with a series of mutations with random fitnesses. In the first model, the population is allowed to reach equilibrium before mutation resumes; in the second the iterations and mutation occur simultaneously. Monte Carlo simulations of these models show that viability selection is easily able to maintain stable 6- or 7-allele polymorphisms and that monomorphisms and diallelic polymorphisms are uncommon. The question of how monomorphisms arise is also discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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