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. 1960 Jul;76(1):109–116. doi: 10.1042/bj0760109

Toxic liver injury. Inhibition by dimethylnitrosamine of incorporation of labelled amino acids into proteins of rat-liver preparations in vitro

T Hultin 1, E Arrhenius 1, H Löw 1, P N Magee 1,*
PMCID: PMC1204607  PMID: 14403971

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAILIE M. J., CHRISTIE G. S. The acute toxic action of dimethylnitrosamine on liver cells. Biochem J. 1959 Jul;72:473–479. doi: 10.1042/bj0720473. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BARNES J. M., MAGEE P. N. Some toxic properties of dimethylnitrosamine. Br J Ind Med. 1954 Jul;11(3):167–174. doi: 10.1136/oem.11.3.167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BOYLAND E. Mutagens. Pharmacol Rev. 1954 Sep;6(3):345–364. [PubMed] [Google Scholar]
  4. BOYLAND E. Mutagens. Pharmacol Rev. 1954 Sep;6(3):345–364. [PubMed] [Google Scholar]
  5. BRODIE B. B., AXELROD J., COOPER J. R., GAUDETTE L., LA DU B. N., MITOMA C., UDENFRIEND S. Detoxication of drugs and other foreign compounds by liver microsomes. Science. 1955 Apr 22;121(3147):603–604. doi: 10.1126/science.121.3147.603. [DOI] [PubMed] [Google Scholar]
  6. Cohn W. E. The Separation of Purine and Pyrimidine Bases and of Nucleotides by Ion Exchange. Science. 1949 Apr 15;109(2833):377–378. doi: 10.1126/science.109.2833.377. [DOI] [PubMed] [Google Scholar]
  7. DUTTON A. H., HEATH D. F. Demethylation of dimethylnitrosamine in rats and mice. Nature. 1956 Sep 22;178(4534):644–644. doi: 10.1038/178644a0. [DOI] [PubMed] [Google Scholar]
  8. ERNSTER L., LINDBERG O. Determination of organic phosphorus compounds by phosphate analysis. Methods Biochem Anal. 1956;3:1–22. doi: 10.1002/9780470110195.ch1. [DOI] [PubMed] [Google Scholar]
  9. ERNSTER L., LOW H. Reconstruction of oxidative phosphorylation in aged mitochondrial systems. Exp Cell Res. 1955;(Suppl 3):133–153. [PubMed] [Google Scholar]
  10. FRISELL W. R., MACKENZIE C. G. The binding sites of sarcosine oxidase. J Biol Chem. 1955 Nov;217(1):275–285. [PubMed] [Google Scholar]
  11. HEATH D. F., DUTTON A. The detection of metabolic products from dimethylnitrosamine in rats and mice. Biochem J. 1958 Dec;70(4):619–626. doi: 10.1042/bj0700619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HOAGLAND M. B., KELLER E. B., ZAMECNIK P. C. Enzymatic carboxyl activation of amino acids. J Biol Chem. 1956 Jan;218(1):345–358. [PubMed] [Google Scholar]
  13. HULTIN T. The distribution of protein-bound azo dye in subfractions of liver cytoplasm fractions. Exp Cell Res. 1956 Jun;10(3):697–703. doi: 10.1016/0014-4827(56)90047-7. [DOI] [PubMed] [Google Scholar]
  14. HULTIN T., VON DER DECKEN A. The activity of soluble cytoplasmic constituents from regenerating rat liver in amino acid incorporating systems. Exp Cell Res. 1958 Dec;15(3):581–594. doi: 10.1016/0014-4827(58)90106-x. [DOI] [PubMed] [Google Scholar]
  15. JENSEN K. A., KIRK I., KØLMARK G., WESTERGAARD M. Chemically induced mutations in Neurospora. Cold Spring Harb Symp Quant Biol. 1951;16:245–261. doi: 10.1101/sqb.1951.016.01.020. [DOI] [PubMed] [Google Scholar]
  16. LOW H. On the participation of flavin in mitochondrial adenosine triphosphatase reactions. Biochim Biophys Acta. 1959 Mar;32(1):1–10. doi: 10.1016/0006-3002(59)90547-5. [DOI] [PubMed] [Google Scholar]
  17. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  18. MAGEE P. N., BARNES J. M. The experimental production of tumours in the rat by dimethylnitrosamine (N-nitroso dimethylamine). Acta Unio Int Contra Cancrum. 1959;15(1):187–190. [PubMed] [Google Scholar]
  19. MAGEE P. N., BARNES J. M. The production of malignant primary hepatic tumours in the rat by feeding dimethylnitrosamine. Br J Cancer. 1956 Mar;10(1):114–122. doi: 10.1038/bjc.1956.15. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. MAGEE P. N. Toxic liver injury; inhibition of protein synthesis in rat liver by dimethylnitrosamine in vivo. Biochem J. 1958 Dec;70(4):606–611. doi: 10.1042/bj0700606. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. MAGEE P. N. Toxic liver injury; the metabolism of dimethylnitrosamine. Biochem J. 1956 Dec;64(4):676–682. doi: 10.1042/bj0640676. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. MAGEE P. N., VANDEKAR M. Toxic liver injury; the metabolism of dimethylnitrosamine in vitro. Biochem J. 1958 Dec;70(4):600–605. doi: 10.1042/bj0700600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. OHLMEYER P. A new coenzyme of alcoholic fermentation. J Biol Chem. 1951 May;190(1):21–30. [PubMed] [Google Scholar]
  24. VON DER DECKEN A., HULTIN T. The activity of microsomes from regenerating rat liver in amino acid incoporating systems. Exp Cell Res. 1958 Feb;14(1):88–96. doi: 10.1016/0014-4827(58)90216-7. [DOI] [PubMed] [Google Scholar]
  25. ZAMECNIK P. C., KELLER E. B. Relation between phosphate energy donors and incorporation of labeled amino acids into proteins. J Biol Chem. 1954 Jul;209(1):337–354. [PubMed] [Google Scholar]
  26. ZIEGLER D. M., MELCHIOR J. B. Activation of the amino acid-incorporating system of rat liver slices upon incubation. J Biol Chem. 1955 Dec;217(2):569–577. [PubMed] [Google Scholar]

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