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. 1991 Nov;129(3):669–673. doi: 10.1093/genetics/129.3.669

Seven-Base-Pair Inverted Repeats in DNA Form Stable Hairpins in Vivo in Saccharomyces Cerevisiae

D K Nag 1, T D Petes 1
PMCID: PMC1204734  PMID: 1752412

Abstract

Palindromic sequences in single-stranded DNA and RNA have the potential for intrastrand base pairing, resulting in formation of ``hairpin'' structures. We previously reported a genetic method for detecting such structures in vivo in the yeast Saccharomyces cerevisiae. Below, we describe evidence indicating that a 14-base-pair palindrome (7 bp per inverted repeat) is sufficient for formation of a hairpin in vivo.

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Selected References

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