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. 1993 Oct;135(2):297–308. doi: 10.1093/genetics/135.2.297

Mixed Segregation and Recombination of Chromosomes and Yacs during Single-Division Meiosis in Spo13 Strains of Saccharomyces Cerevisiae

Y Hugerat 1, G Simchen 1
PMCID: PMC1205636  PMID: 8243995

Abstract

Diploid yeast strains, homozygous for the mutation spo13, undergo a single-division meiosis and form dyads (two spores held together in one ascus). Dyad analysis of spo13/spo13 strains with centromere-linked markers on five different chromosomes and on a pair of human DNA YACs shows that: (a) in spo13 meiosis, chromosomes undergo mixed segregation, namely some chromosomes segregate reductionally whereas others, in the same cell, segregate equationally; (b) different chromosomes exhibit different segregation tendencies; (c) recombination between homologous chromosomes might not determine that a bivalent undergoes reductional rather than equational segregation.

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Selected References

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