Abstract
In this paper we study the process of allele frequency change in finite populations with overlapping generations with the purpose of evaluating the possibility of estimating the effective size from observations of temporal frequency shifts of selectively neutral alleles. Focusing on allele frequency changes between successive cohorts (individuals born in particular years), we show that such changes are not determined by the effective population size alone, as they are when generations are discrete. Rather, in populations with overlapping generations, the amount of temporal allele frequency change is dependent on the age-specific survival and birth rates. Taking this phenomenon into account, we present an estimator for effective size that can be applied to populations with overlapping generations.
Full Text
The Full Text of this article is available as a PDF (2.3 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Choy S. C., Weir B. S. Exact inbreeding coefficients in populations with overlapping generations. Genetics. 1978 Jul;89(3):591–614. doi: 10.1093/genetics/89.3.591. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Emigh T. H. The dynamics of finite haploid populations with overlapping generations. I. Moments, fixation probabilities and stationary distributions. Genetics. 1979 May;92(1):323–337. doi: 10.1093/genetics/92.1.323. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Felsenstein J. Inbreeding and variance effective numbers in populations with overlapping generations. Genetics. 1971 Aug;68(4):581–597. doi: 10.1093/genetics/68.4.581. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johnson D. L. Inbreeding in populations with overlapping generations. Genetics. 1977 Nov;87(3):581–591. doi: 10.1093/genetics/87.3.581. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tajima F., Nei M. Note on genetic drift and estimation of effective population size. Genetics. 1984 Mar;106(3):569–574. doi: 10.1093/genetics/106.3.569. [DOI] [PMC free article] [PubMed] [Google Scholar]