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. 1965 Mar;94(3):778–782. doi: 10.1042/bj0940778

Steroid metabolism in the cat. Biliary and urinary excretion of metabolites of [4-14C]testosterone

Susan E H Archer 1, T Scratcherd 1, W Taylor 1
PMCID: PMC1206617  PMID: 16749072

Abstract

1. [4-14C]Testosterone was administered intravenously to anaesthetized male cats as a single injection or as a 45–60min. infusion. 2. Most of the administered radioactivity was excreted in the bile (70–80%); only 2·9–5·5% of the dose was excreted in the urine. 3. Bile and urine samples were hydrolysed successively to yield glucuronide, `cold-acid-hydrolysed' and `hot-acid-hydrolysed' fractions. 4. The proportion of glucuronides in bile decreased in successive samples, but cold-and hot-acid-hydrolysed metabolites showed no consistent change. 5. After hydrolysis most of the radioactivity in both bile and urine could not be extracted by ether from neutral aqueous solution.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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