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. 1965 Jun;95(3):803–810. doi: 10.1042/bj0950803

Rate of utilization of glucose and `compartmentation' of α-oxoglutarate and glutamate in rat brain

M K Gaitonde 1
PMCID: PMC1206810  PMID: 14342519

Abstract

1. The rate of incorporation of 14C into pyruvate, α-oxoglutarate, lactate and glucose of rat tissues was measured after the subcutaneous injection of uniformly labelled glucose. 2. In rat brain the specific radioactivities of lactate and glucose were similar to that of alanine. In liver the specific radioactivity of glucose was considerably higher than that of lactate or alanine. 3. The specific radioactivities of α-oxo acids of rat brain were lower than those of corresponding amino acids, alanine and glutamate. These findings have been explained in relation to metabolic compartments in vivo. 4. The approximate estimated rate of glucose utilization in rat brain in vivo is 0·96μmole/g. of brain/min.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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