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. 1995 Dec;141(4):1633–1639. doi: 10.1093/genetics/141.4.1633

Analysis of Conditional Genetic Effects and Variance Components in Developmental Genetics

J Zhu 1
PMCID: PMC1206893  PMID: 8601500

Abstract

A genetic model with additive-dominance effects and genotype X environment interactions is presented for quantitative traits with time-dependent measures. The genetic model for phenotypic means at time t conditional on phenotypic means measured at previous time (t - 1) is defined. Statistical methods are proposed for analyzing conditional genetic effects and conditional genetic variance components. Conditional variances can be estimated by minimum norm quadratic unbiased estimation (MINQUE) method. An adjusted unbiased prediction (AUP) procedure is suggested for predicting conditional genetic effects. A worked example from cotton fruiting data is given for comparison of unconditional and conditional genetic variances and additive effects.

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