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. 1996 Feb;142(2):459–470. doi: 10.1093/genetics/142.2.459

Rearrangements Involving Repeated Sequences within a P Element Preferentially Occur between Units Close to the Transposon Extremities

F Paques 1, B Bucheton 1, M Wegnez 1
PMCID: PMC1206980  PMID: 8852845

Abstract

In a previous report we described rearrangements occurring at a high rate (30% of the progeny of dysgenic flies) within a cluster of 5S genes internal to a P element. These events were characterized as precise amplifications and deletions of 5S units. Here we analyze recombination events within P elements containing two repeated arrays of 5S genes flanking a central white gene. Deletions (50%) and duplications (3%) of the white gene together with various amounts of flanking 5S genes were observed. These recombinations occur preferentially between the most external 5S units of P transposons. Such rearrangements could be favored by interactions between the proteins bound to the P terminal sequences.

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Selected References

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