Abstract
Several estimators of population differentiation have been proposed in the recent past to deal with various types of genetic markers (i.e., allozymes, nucleotide sequences, restriction fragment length polymorphisms, or microsatellites). We discuss the relationships among these estimators and show how a single analysis of variance framework can accomodate these qualitatively different data types.
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Selected References
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- Excoffier L., Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol. 1995 Sep;12(5):921–927. doi: 10.1093/oxfordjournals.molbev.a040269. [DOI] [PubMed] [Google Scholar]
- Excoffier L., Smouse P. E., Quattro J. M. Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. Genetics. 1992 Jun;131(2):479–491. doi: 10.1093/genetics/131.2.479. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hudson R. R., Slatkin M., Maddison W. P. Estimation of levels of gene flow from DNA sequence data. Genetics. 1992 Oct;132(2):583–589. doi: 10.1093/genetics/132.2.583. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Long J. C. The allelic correlation structure of Gainj- and Kalam-speaking people. I. The estimation and interpretation of Wright's F-statistics. Genetics. 1986 Mar;112(3):629–647. doi: 10.1093/genetics/112.3.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Long J. C., Williams R. C., Urbanek M. An E-M algorithm and testing strategy for multiple-locus haplotypes. Am J Hum Genet. 1995 Mar;56(3):799–810. [PMC free article] [PubMed] [Google Scholar]
- Lynch M., Crease T. J. The analysis of population survey data on DNA sequence variation. Mol Biol Evol. 1990 Jul;7(4):377–394. doi: 10.1093/oxfordjournals.molbev.a040607. [DOI] [PubMed] [Google Scholar]
- Nei M. Analysis of gene diversity in subdivided populations. Proc Natl Acad Sci U S A. 1973 Dec;70(12):3321–3323. doi: 10.1073/pnas.70.12.3321. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Richardson R. H., Smouse P. E. Patterns of molecular variation. I. Interspecific comparisons of electromorphs in the Drosophila mulleri complex. Biochem Genet. 1976 Jun;14(5-6):447–466. doi: 10.1007/BF00486126. [DOI] [PubMed] [Google Scholar]
- Richardson R. H., Smouse P. E., Richardson M. E. Patterns of molecular variation. II. associations of electrophoretic mobility and larval substrate within species of the Drosophila mulleri complex. Genetics. 1977 Jan;85(1):141–154. doi: 10.1093/genetics/85.1.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Takahata N., Palumbi S. R. Extranuclear differentiation and gene flow in the finite island model. Genetics. 1985 Feb;109(2):441–457. doi: 10.1093/genetics/109.2.441. [DOI] [PMC free article] [PubMed] [Google Scholar]