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. 1996 May;143(1):353–364. doi: 10.1093/genetics/143.1.353

Genetics of Differences in Pheromonal Hydrocarbons between Drosophila Melanogaster and D. Simulans

J A Coyne 1
PMCID: PMC1207267  PMID: 8722787

Abstract

Females of Drosophila melanogaster and its sibling species D. simulans have very different cuticular hydrocarbons, with the former bearing predominantly 7,11-heptacosadiene and the latter 7-tricosene. This difference contributes to reproductive isolation between the species. Genetic analysis shows that this difference maps to only the third chromosome, with the other three chromosomes having no apparent effect. The D. simulans alleles on the left arm of chromosome 3 are largely recessive, allowing us to search for the relevant regions using D. melanogaster deficiencies. At least four nonoverlapping regions of this arm have large effects on the hydrocarbon profile, implying that several genes on this arm are responsible for the species difference. Because the right arm of chromosome 3 also affects the hydrocarbon profile, a minimum of five genes appear to be involved. The large effect of the thrid chromosome on hydrocarbons has also been reported in the hybridization between D. simulans and its closer relative D. sechellia, implying either an evolutionary convergence or the retention in D. sechellia of an ancestral sexual dimorphism.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Coyne J. A., Aulard S., Berry A. Lack of underdominance in a naturally occurring pericentric inversion in Drosophila melanogaster and its implications for chromosome evolution. Genetics. 1991 Nov;129(3):791–802. doi: 10.1093/genetics/129.3.791. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Coyne J. A., Crittenden A. P., Mah K. Genetics of a pheromonal difference contributing to reproductive isolation in Drosophila. Science. 1994 Sep 2;265(5177):1461–1464. doi: 10.1126/science.8073292. [DOI] [PubMed] [Google Scholar]
  3. Coyne J. A. Genetics and speciation. Nature. 1992 Feb 6;355(6360):511–515. doi: 10.1038/355511a0. [DOI] [PubMed] [Google Scholar]
  4. Coyne J. A., Oyama R. Localization of pheromonal sexual dimorphism in Drosophila melanogaster and its effect on sexual isolation. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9505–9509. doi: 10.1073/pnas.92.21.9505. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Ferveur J. F., Jallon J. M. Genetic control of pheromones in Drosophila simulans. II. kété, a locus on the X chromosome. Genetics. 1993 Mar;133(3):561–567. doi: 10.1093/genetics/133.3.561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Jallon J. M. A few chemical words exchanged by Drosophila during courtship and mating. Behav Genet. 1984 Sep;14(5):441–478. doi: 10.1007/BF01065444. [DOI] [PubMed] [Google Scholar]
  7. Kliman R. M., Hey J. DNA sequence variation at the period locus within and among species of the Drosophila melanogaster complex. Genetics. 1993 Feb;133(2):375–387. doi: 10.1093/genetics/133.2.375. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ohnishi S., Leigh Brown A. J., Voelker R. A., Langley C. H. Estimation of genetic variability in natural populations of Drosophila simulans by two-dimensional and starch gel electrophoresis. Genetics. 1982 Jan;100(1):127–136. doi: 10.1093/genetics/100.1.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Orr H. A. Mapping and characterization of a 'speciation gene' in Drosophila. Genet Res. 1992 Apr;59(2):73–80. doi: 10.1017/s0016672300030275. [DOI] [PubMed] [Google Scholar]
  10. Pechine J. M., Perez F., Antony C., Jallon J. M. A further characterization of Drosophila cuticular monoenes using a mass spectrometry method to localize double bonds in complex mixtures. Anal Biochem. 1985 Feb 15;145(1):177–182. doi: 10.1016/0003-2697(85)90344-6. [DOI] [PubMed] [Google Scholar]
  11. Perez D. E., Wu C. I., Johnson N. A., Wu M. L. Genetics of reproductive isolation in the Drosophila simulans clade: DNA marker-assisted mapping and characterization of a hybrid-male sterility gene, Odysseus (Ods). Genetics. 1993 May;134(1):261–275. doi: 10.1093/genetics/134.1.261. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Roelofs W., Glover T., Tang X. H., Sreng I., Robbins P., Eckenrode C., Löfstedt C., Hansson B. S., Bengtsson B. O. Sex pheromone production and perception in European corn borer moths is determined by both autosomal and sex-linked genes. Proc Natl Acad Sci U S A. 1987 Nov;84(21):7585–7589. doi: 10.1073/pnas.84.21.7585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Sturtevant A H. Genetic Studies on DROSOPHILA SIMULANS. I. Introduction. Hybrids with DROSOPHILA MELANOGASTER. Genetics. 1920 Sep;5(5):488–500. doi: 10.1093/genetics/5.5.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Turelli M., Orr H. A. The dominance theory of Haldane's rule. Genetics. 1995 May;140(1):389–402. doi: 10.1093/genetics/140.1.389. [DOI] [PMC free article] [PubMed] [Google Scholar]

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