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. 1996 Dec;144(4):1665–1671.

Segregation Distortion in Drosophila Melanogaster: Genomic Organization of Responder Sequences

R Moschetti 1, R Caizzi 1, S Pimpinelli 1
PMCID: PMC1207717  PMID: 8978053

Abstract

The heterochromatic Responder (Rsp) locus of Drosophila melanogaster is the target of the two distorter loci Sd and E(SD). Rsp is located in a specific heterochromatic region of the second chromosome and is made up of AT-rich satellite sequences whose abundance is related to its sensitivity to the distorter chromosomes. Here we report that a cluster of Rsp sequences is also located in the third chromosome. The third-chromosome cluster has the same flanking sequences as the clone originally used to identify the Rsp elements, and one of the flanking sequences is a rearranged 412 retrotrsansposon. The presence of a second, unlinked Rsp-sequence cluster makes re-interpretation necessary for some earlier experiments in which segregation of the third chromosome had not been followed and raises interesing possibilities for the origin of the Rsp locus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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