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. 1972 Dec;72(4):615–638. doi: 10.1093/genetics/72.4.615

Lethality Patterns and Morphology of Selected Lethal and Semi-Lethal Mutations in the Zeste-White Region of DROSOPHILA MELANOGASTER

M P Shannon 1, T C Kaufman 1, M W Shen 1, B H Judd 1
PMCID: PMC1212859  PMID: 4631596

Abstract

Aspects of the developmental genetics of lethal and semi-lethal mutants representing 13 complementation groups (cistrons) in the 3A–3C region of the X chromosome of Drosophila melanogaster are given. Each of these cistrons is associated with a particular chromomere in the salivary gland chromosome. Mutants within each cistron have similar lethality patterns and morphological attributes, and the characteristics of a given cistron are distinct with respect to other cistrons. These results provide additional evidence that only one function is associated with each chromomere.—The results of the lethality pattern analysis are also compared with previous studies of lethal mutants of Drosophila.

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Selected References

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  1. Brehme K S. A Study of the Effect on Development of "Minute" Mutations in Drosophila Melanogaster. Genetics. 1939 Mar;24(2):131–161. doi: 10.1093/genetics/24.2.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Judd B. H., Shen M. W., Kaufman T. C. The anatomy and function of a segment of the X chromosome of Drosophila melanogaster. Genetics. 1972 May;71(1):139–156. doi: 10.1093/genetics/71.1.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Kaliss N. The Effect on Development of a Lethal Deficiency in Drosophila Melanogaster: With a Description of the Normal Embryo at the Time of Hatching. Genetics. 1939 Mar;24(2):244–270. doi: 10.1093/genetics/24.2.244. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lefevre G., Jr, Green M. M. Genetic duplication in the white-split interval of the X chromosome in Drosophila melanogaster. Chromosoma. 1972;36(4):391–412. doi: 10.1007/BF00336795. [DOI] [PubMed] [Google Scholar]
  5. Lefevre G., Jr, Wilkins M. D. Cytogenetic studies on the white locus in Drosophila melanogaster. Genetics. 1966 Jan;53(1):175–187. doi: 10.1093/genetics/53.1.175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. OSTER I. I. Time of death of sex-linked lethals of different origins in Drosophila melanogaster. Nature. 1954 Mar 27;173(4404):594–595. doi: 10.1038/173594a0. [DOI] [PubMed] [Google Scholar]

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