Abstract
A mutant strain of pneumococcus which fails to discriminate against low-efficiency markers during transformation by homospecific pneumococcal donor DNA retains the wild-type capacity to discriminate against heterospecific (streptococcal) donor DNA. We conclude that discrimination against heterospecific DNA must differ from that against low-efficiency markers by the kind or number of elements being recognized.
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Selected References
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- Biswas G. D., Ravin A. W. Heterospecific transformation of Pneumococcus and Streptococcus. IV. Variations in hybrid DNA produced by recombination. Mol Gen Genet. 1971;110(1):1–22. doi: 10.1007/BF00276040. [DOI] [PubMed] [Google Scholar]
- Gurney T., Jr, Fox M. S. Physical and genetic hybrids formed in bacterial transformation. J Mol Biol. 1968 Feb 28;32(1):83–100. doi: 10.1016/0022-2836(68)90147-2. [DOI] [PubMed] [Google Scholar]
- Lacks S. Integration efficiency and genetic recombination in pneumococcal transformation. Genetics. 1966 Jan;53(1):207–235. doi: 10.1093/genetics/53.1.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peterson J. M., Guild W. R. Fractionated strands of bacterial deoxyribonucleic acid. 3. Transformation efficiencies and rates of phenotypic expression. J Bacteriol. 1968 Dec;96(6):1991–1996. doi: 10.1128/jb.96.6.1991-1996.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SCHAEFFER P. Interspecific reactions in bacterial transformation. Symp Soc Exp Biol. 1958;12:60–74. [PubMed] [Google Scholar]
- Sicard A. M., Ephrussi-Taylor H. Genetic recombination in DNA-induced transformation of Pneumococcus. II. Mapping the amiA region. Genetics. 1965 Dec;52(6):1207–1227. doi: 10.1093/genetics/52.6.1207. [DOI] [PMC free article] [PubMed] [Google Scholar]
