Skip to main content
Genetics logoLink to Genetics
. 1973 Sep;75(1):19–22. doi: 10.1093/genetics/75.1.19

The Apparent Conservation of the Internal Low Efficiency Promoter of the Tryptophan Operons of Several Species of ENTEROBACTERIACEAE

Michael Largen 1, William Belser 1
PMCID: PMC1212995  PMID: 4587116

Abstract

The specific activities of the tryptophan biosynthetic enzymes were determined for eleven different species of Enterobacteriaceae grown under repressing and non-repressing conditions. In all the bacteria examined the multipliciy of derepression for the first two enzymes of the pathway was at least twofold greater than the multiplicity of derepression for the last three enzymes.

Full Text

The Full Text of this article is available as a PDF (266.4 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bauerle R. H., Margolin P. The functional organization of the tryptophan gene cluster in Salmonella typhimurium. Proc Natl Acad Sci U S A. 1966 Jul;56(1):111–118. doi: 10.1073/pnas.56.1.111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Jackson E. N., Yanofsky C. Internal promoter of the tryptophan operon of Escherichia coli is located in a structural gene. J Mol Biol. 1972 Aug 21;69(2):307–313. doi: 10.1016/0022-2836(72)90232-x. [DOI] [PubMed] [Google Scholar]
  3. Morse D. E., Yanofsky C. The internal low-efficiency promoter of the tryptophan operon of Escherichia coli. J Mol Biol. 1968 Dec;38(3):447–451. doi: 10.1016/0022-2836(68)90401-4. [DOI] [PubMed] [Google Scholar]
  4. Scaife J., Beckwith J. R. Mutational alteration of the maximal level of Lac operon expression. Cold Spring Harb Symp Quant Biol. 1966;31:403–408. doi: 10.1101/sqb.1966.031.01.052. [DOI] [PubMed] [Google Scholar]
  5. VOGEL H. J., BONNER D. M. Acetylornithinase of Escherichia coli: partial purification and some properties. J Biol Chem. 1956 Jan;218(1):97–106. [PubMed] [Google Scholar]
  6. Wuesthoff G., Bauerle R. H. Mutations creating internal promoter elements in the tryptophan operon of Salmonella typhimurium. J Mol Biol. 1970 Apr 14;49(1):171–196. doi: 10.1016/0022-2836(70)90384-0. [DOI] [PubMed] [Google Scholar]
  7. YANOFSKY C., LENNOX E. S. Transduction and recombination study of linkage relationships among the genes controlling tryptophan synthesis in Escherichia coli. Virology. 1959 Aug;8:425–447. doi: 10.1016/0042-6822(59)90046-7. [DOI] [PubMed] [Google Scholar]
  8. Yanofsky C. Gene structure and protein structure. Harvey Lect. 1967;61:145–168. [PubMed] [Google Scholar]

Articles from Genetics are provided here courtesy of Oxford University Press

RESOURCES