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. 1973 Dec;75(4):663–670. doi: 10.1093/genetics/75.4.663

Chromosome Markers in MUS MUSCULUS: Strain Differences in C-Banding

V G Dev 1, D A Miller 1, O J Miller 1
PMCID: PMC1213039  PMID: 4778788

Abstract

The mitotic chromosomes of several inbred strains of mice and a series of F1 hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F1 hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allderdice P. W., Miller O. J., Pearson P. L., Klein G., Harris H. Human chromosomes in 18 man-mouse somatic hybrid cell lines analysed by quinacrine fluorescence. J Cell Sci. 1973 May;12(3):809–830. doi: 10.1242/jcs.12.3.809. [DOI] [PubMed] [Google Scholar]
  2. Chen T. R., Ruddle F. H. Karyotype analysis utilizing differentially stained constitutive heterochromatin of human and murine chromosomes. Chromosoma. 1971;34(1):51–72. doi: 10.1007/BF00285516. [DOI] [PubMed] [Google Scholar]
  3. Craig-Holmes A. P., Moore F. B., Shaw M. W. Polymorphism of human C-band heterochromatin. I. Frequency of variants. Am J Hum Genet. 1973 Mar;25(2):181–192. [PMC free article] [PubMed] [Google Scholar]
  4. Dev V. G., Miller D. A., Allderdice P. W., Miller O. J. Method for locating the centromeres of mouse meiotic chromosomes and its application to T163H and T70H translocations. Exp Cell Res. 1972 Jul;73(1):259–262. doi: 10.1016/0014-4827(72)90132-2. [DOI] [PubMed] [Google Scholar]
  5. Duffey P. A. Chromosome variation in Peromyscus: a new mechanism. Science. 1972 Jun 23;176(4041):1333–1334. doi: 10.1126/science.176.4041.1333. [DOI] [PubMed] [Google Scholar]
  6. Eicher E. M. The identification of the chromosome bearing linkage group XII in the mouse. Genetics. 1971 Oct;69(2):267–271. doi: 10.1093/genetics/69.2.267. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Miller O. J., Miller D. A., Kouri R. E., Allderdice P. W., Dev V. G., Grewal M. S., Hutton J. J. Identification of the mouse karyotype by quinacrine fluorescence, and tentative assignment of seven linkage groups. Proc Natl Acad Sci U S A. 1971 Jul;68(7):1530–1533. doi: 10.1073/pnas.68.7.1530. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Southern E. M. Base sequence and evolution of guinea-pig alpha-satellite DNA. Nature. 1970 Aug 22;227(5260):794–798. doi: 10.1038/227794a0. [DOI] [PubMed] [Google Scholar]

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