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. 1974 Apr;76(4):837–848. doi: 10.1093/genetics/76.4.837

A General Model to Account for Enzyme Variation in Natural Populations

John H Gillespie 1,2, Charles H Langley 1,2
PMCID: PMC1213108  PMID: 4838763

Abstract

Approximate conditions for genetic polymorphism in temporally and spatially varying environments are presented for loci which are intermediate at the level of fitness or at the level of gene function. The conditions suggest that polymorphism will be more likely in more variable environments while unlikely in constant environments. Biochemical evidence is presented to justify the assumption of heterozygote intermediacy. Observations on natural populations are cited which substantiate the claim that allozymic polymorphism is primarily due to selection acting on environmental variation in gene function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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