Skip to main content
Genetics logoLink to Genetics
. 1975 Jan;79(1):55–61. doi: 10.1093/genetics/79.1.55

Effects of Sr-Spirochete Infection on DROSOPHILA MELANOGASTER Carrying Intersex Genes

Chieko Miyamoto 1, Kugao Oishi 1
PMCID: PMC1213258  PMID: 805080

Abstract

Three sex-transforming genes (ix, traD, and dsx) in D. melanogaster were examined with respect to possible interactions with the NSR strain of SR-spirochetes. The SR-spirochetes exerted a lethal effect on XY but not on XX individuals, regardless of whether they were phenotypically males, intersexes, or females. These results, taken together with those reported by Sakaguchi and Poulson (1963) on tra and 2X3A intersexes, both of which are resistant to the androcidal action of SR-spirochetes, support the interpretation that male susceptibility is a consequence of the single X condition.

Full Text

The Full Text of this article is available as a PDF (405.7 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown E H, King R C. Studies on the Expression of the Transformer Gene of Drosophila Melanogaster. Genetics. 1961 Feb;46(2):143–156. doi: 10.1093/genetics/46.2.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Counce S. J., Poulson D. F. The expression of maternally-transmitted sex ratio condition (SR) in two strains of Drosophila melanogaster. Genetica. 1966;37(3):364–390. doi: 10.1007/BF01547143. [DOI] [PubMed] [Google Scholar]
  3. HILDRETH P. E. DOUBLESEX, RECESSIVE GENE THAT TRANSFORMS BOTH MALES AND FEMALES OF DROSOPHILA INTO INTERSEXES. Genetics. 1965 Apr;51:659–678. doi: 10.1093/genetics/51.4.659. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Oishi K., Poulson D. F. A virus associated with SR-spirochetes of Drosophila nebulosa. Proc Natl Acad Sci U S A. 1970 Nov;67(3):1565–1572. doi: 10.1073/pnas.67.3.1565. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Oishi K. Spirochaete-mediated abnormal sex-ratio (SR) condition in Drosophila: a second virus associated with spirochaetes and its use in the study of the SR condition. Genet Res. 1971 Aug;18(1):45–56. doi: 10.1017/s0016672300012404. [DOI] [PubMed] [Google Scholar]
  6. SAKAGUCHI B., OISHI K., KOBAYASHI S. INTERFERENCE BETWEEN "SEX-RATIO" AGENTS OF DROSOPHILA WILLISTONI AND DROSOPHILA NEBULOSA. Science. 1965 Jan 8;147(3654):160–162. doi: 10.1126/science.147.3654.160. [DOI] [PubMed] [Google Scholar]
  7. Sakaguchi B, Poulson D F. Interspecific Transfer of the "Sex-Ratio" Condition from Drosophila Willistoni to D. Melanogaster. Genetics. 1963 Jun;48(6):841–861. doi: 10.1093/genetics/48.6.841. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Shearn A., Rice T., Garen A., Gehring W. Imaginal disc abnormalities in lethal mutants of Drosophila. Proc Natl Acad Sci U S A. 1971 Oct;68(10):2594–2598. doi: 10.1073/pnas.68.10.2594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Smith P. D., Lucchesi J. C. The role of sexuality in dosage compensation in Drosophila. Genetics. 1969 Mar;61(3):607–618. doi: 10.1093/genetics/61.3.607. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Genetics are provided here courtesy of Oxford University Press

RESOURCES