Skip to main content
Genetics logoLink to Genetics
. 1976 Jan;82(1):9–17. doi: 10.1093/genetics/82.1.9

Complementation Analysis of Linked Circadian Clock Mutants of NEUROSPORA CRASSA

Jerry F Feldman 1,2, Marian N Hoyle 1,2
PMCID: PMC1213448  PMID: 129346

Abstract

A fourth mutant of Neurospora crassa, designated frq-4, has been isolated in which the period length of the circadian conidiation rhythm is shortened to 19.3 ± 0.3 hours. This mutant is tightly linked to the three previously isolated frq mutants, and all four map to the right arm of linkage group VII about 10 map units from the centromere. Complementation tests suggest, but do not prove, that all four mutations are allelic, since each of the four mutants is co-dominant with the frq+ allele—i.e., heterokaryons have period lengths intermediate between the mutant and wild-type—and since heterokaryons between pairs of mutants also have period lengths intermediate between those of the two mutants.

Full Text

The Full Text of this article is available as a PDF (443.5 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bruce V. G. Mutants of the biological clock in Chlamydomonas reinhardi. Genetics. 1972 Apr;70(4):537–548. doi: 10.1093/genetics/70.4.537. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Feldman J. F., Hoyle M. N. Isolation of circadian clock mutants of Neurospora crassa. Genetics. 1973 Dec;75(4):605–613. doi: 10.1093/genetics/75.4.605. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Konopka R. J., Benzer S. Clock mutants of Drosophila melanogaster. Proc Natl Acad Sci U S A. 1971 Sep;68(9):2112–2116. doi: 10.1073/pnas.68.9.2112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lehman J. F., Gleason M. K., Ahlgren S. K., Metzenberg R. L. Regulation of phosphate metabolism in Neurospora crassa. Characterization of regulatory mutants. Genetics. 1973 Sep;75(1):61–73. doi: 10.1093/genetics/75.1.61. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Genetics are provided here courtesy of Oxford University Press

RESOURCES