Abstract
A meiotic fine structure map of a yeast tyrosine-inserting ochre suppressor, SUP3-o, was constructed. This was accomplished by examining ten intragenic suppressor-inactive revertants for their relationship to each other and to the original SUP3-o mutation. The second-site revertants map on both sides of the SUP3-o mutation. The meiotic map length based on the summation of short intervals is 45+/10 5 asci.
Full Text
The Full Text of this article is available as a PDF (585.1 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Capecchi M. R., Hughes S. H., Wahl G. M. Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro. Cell. 1975 Nov;6(3):269–277. doi: 10.1016/0092-8674(75)90178-6. [DOI] [PubMed] [Google Scholar]
- Garen A., Garen S., Wilhelm R. C. Suppressor genes for nonsense mutations. I. The Su-1, Su-2 and Su-3 genes of Escherichia coli. J Mol Biol. 1965 Nov;14(1):167–178. doi: 10.1016/s0022-2836(65)80238-8. [DOI] [PubMed] [Google Scholar]
- Gesteland R. F., Wolfner M., Grisafi P., Fink G., Botstein D., Roth J. R. Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA. Cell. 1976 Mar;7(3):381–390. doi: 10.1016/0092-8674(76)90167-7. [DOI] [PubMed] [Google Scholar]
- Piper P. W., Wasserstein M., Engbaek F., Kaltoft K., Celis J. E., Zeuthen J., Liebman S., Sherman F. Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon. Nature. 1976 Aug 26;262(5571):757–761. doi: 10.1038/262757a0. [DOI] [PubMed] [Google Scholar]
- Rasse-Messenguy F., Fink G. R. Temperature-sensitive nonsense suppressors in yeast. Genetics. 1973 Nov;75(3):459–464. doi: 10.1093/genetics/75.3.459. [DOI] [PMC free article] [PubMed] [Google Scholar]