Abstract
Survival and unscheduled DNA synthesis (UDS) were measured in a cultured insect cell line, TN-368, and a cultured mammalian cell line, V-79-4, following exposure to several fluences of ultraviolet light. TN-368 cells were approximately seven times more resistant to the lethal effects of UV than V-79 cells, as determined by colony formation. The amount of UDS per unit amount of DNA is about the same in both cell types 4 hr after 10–50 J/m2 UV irradiations.
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Selected References
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- Shaeffer J., Merz T. A comparison of unscheduled DNA synthesis, D 0 , cell recovery, and chromosome number in x-irradiated mammalian cell lines. Radiat Res. 1971 Aug;47(2):426–436. [PubMed] [Google Scholar]
- Trosko J. E., Wilder K. Repair of UV-induced pyrimidine dimers in Drosophila melanogaster cells in vitro. Genetics. 1973 Feb;73(2):297–302. doi: 10.1093/genetics/73.2.297. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Walters R. A., Tobey R. A., Hildebrand C. E. Hydroxyurea does not prevent synchronized G1 chinese hamster cells from entering the DNA synthetic period. Biochem Biophys Res Commun. 1976 Mar 8;69(1):212–217. doi: 10.1016/s0006-291x(76)80294-x. [DOI] [PubMed] [Google Scholar]
