Abstract
Mutant strains of Saccharomyces cerevisiae unable to utilize allantoin as sole nitrogen source were isolated and divided into three groups on the basis of their biochemical and genetic characteristics. The three loci associated with these mutant classes were designated dal1 (allantoinase minus), dal2 (allantoicase minus) and dal4 (allantoin transport minus). All three loci are located in a cluster that is proximal to the lys1 locus on the right arm of chromosome IX. The gene order and intergenic distances were estimated to be: dal1—2.5 cM—dal4—1.9 cM—dal2—4.6 cM—lys1.
Full Text
The Full Text of this article is available as a PDF (756.8 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bossinger J., Lawther R. P., Cooper T. G. Nitrogen repression of the allantoin degradative enzymes in Saccharomyces cerevisiae. J Bacteriol. 1974 Jun;118(3):821–829. doi: 10.1128/jb.118.3.821-829.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fink G. R. A cluster of genes controlling three enzymes in histidine biosynthesis in Saccharomyces cerevisiae. Genetics. 1966 Mar;53(3):445–459. doi: 10.1093/genetics/53.3.445. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Perkins D. D. Biochemical Mutants in the Smut Fungus Ustilago Maydis. Genetics. 1949 Sep;34(5):607–626. doi: 10.1093/genetics/34.5.607. [DOI] [PMC free article] [PubMed] [Google Scholar]