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. 1980 Aug;95(4):1013–1022. doi: 10.1093/genetics/95.4.1013

Biochemical Differences between Products of the Adh Locus in Drosophila

John F McDonald 1, Steven M Anderson 1, Mauro Santos 1
PMCID: PMC1214263  PMID: 6781982

Abstract

An analysis of the molecular properties of the major alcohol dehydrogenase (E.C.1.1.1.1) allozyme variants found segregating in natural populations of D. melanogaster is presented. Our results indicate: (1) ADH-S enzyme has generally lower Michaelis-Menten constants than those of ADH-F; (2) ADH-S and ADH-F enzymes display opposite interactions for both co-factor and substrate; and (3) higher levels of ADH are associated with the Adh-fast genotype. The possible adaptive significance of these findings is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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