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. 1980 Aug;95(4):1043–1054. doi: 10.1093/genetics/95.4.1043

The Distribution of Individual Heterozygosity in Natural Populations

Jeffry B Mitton 1,2, Benjamin A Pierce 1,2
PMCID: PMC1214266  PMID: 17249051

Abstract

Estimation of the distribution of the level of individual heterozygosity within natural populations is explored with both Monte-Carlo simulation studies and data from natural populations. Simulations indicate that heterozygosities estimated from as few as a dozen randomly chosen loci may, to some degree, reflect (r = 0.35) heterozygosity determined by 100 independent loci. The shape of the expected distribution of heterozygosity is heavily dependent upon levels of heterozygosity at the loci. Complete genetic data for 12 loci from 997 Fundulus heteroclitus are used to describe the distributions of heterozygosity for different localities, for age classes and for sexes. The distributions deviate from normality. Distributions from different localities are not different, but the distributions are heterogeneous among age classes at one of two localities and are heterogeneous between the sexes.

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Selected References

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