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. 1980 Sep;96(1):201–212. doi: 10.1093/genetics/96.1.201

Organization of the Chorion Genes of BOMBYX MORI, a Multigene Family. III. Detailed Marker Composition of Three Gene Clusters

Marian R Goldsmith 1,2, Eileen Clermont-Rattner 1,2
PMCID: PMC1214289  PMID: 7203009

Abstract

The chorion patterns produced by progeny from crosses that were used to define the linked gene clusters, Ch 1, Ch 2 and Ch 3 (strain C108 vs. strain Ascoli), were examined by two-dimensional gel electrophoresis (isoelectric focusing vs. SDS/urea). Approximately 60 proteins were assigned to four previously defined chorion classes, A, B, C and Hc, believed to represent the products of related genes, on the basis of size and relative cysteine content. All strain-specific markers showed co-dominance in the F1, indicating the likelihood that they are not products of post-translational modification. Twentyseven Ascoli markers co-segregated in testcross progeny, and none of the resolved proteins showed independent assortment, confirming their linkage to chromosome 2. Two-dimensional screening of recombinants demonstrated that all three clusters contain Class A and B markers; Hc markers have been found only in Ch 1 and Ch 2; whereas, mapped C markers were confined to Ch 3. This indicates that chorion clusters are heterogeneous with respect to the markers they contain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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