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. 1981 Mar;97(3-4):731–737. doi: 10.1093/genetics/97.3-4.731

The Inbreeding Effective Population Number and the Expected Homozygosity for an X-Linked Locus

Thomas Nagylaki 1
PMCID: PMC1214421  PMID: 7197653

Abstract

Assuming random mating and discrete nonoverlapping generations, the inbreeding effective population number, (see PDF), is calculated for an X-linked locus. For large populations, the result agrees with the variance effective population number. As an application, the maintenance of genetic variability by the joint action of mutation and random drift is investigated. It is shown that, if every allele mutates at rate u to new types, then the probabilities of identity in state (and hence the expected homozygosity of females) converge to the approximate value (see PDF) at the approximate asymptotic rate (see PDF).

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Selected References

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  1. Wright S. Evolution in Mendelian Populations. Genetics. 1931 Mar;16(2):97–159. doi: 10.1093/genetics/16.2.97. [DOI] [PMC free article] [PubMed] [Google Scholar]

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