Abstract
Three new unusual compound chromosomes have been synthesized in Drosophila melanogaster. They consist of two homologous autosomes joined together in the new order: right arm, left arm, centromere, left arm, right arm, for each of the two major autosomes, and one in which chromosomes 2 and 3 have been combined in the order: right arm of 2, left arm of 2, centromere, left arm of 3, right arm of 3. The attachments of the autosomal arms were accomplished by obtaining chromosome breaks at or very close to the ends of the left arms of the autosomes such that no essential chromosome material has been removed; the compounds derived from them are therefore referred to as entire compounds. These large chromosomes are recovered in progeny with frequencies lower than expectation partly because of zygote mortality associated with these chromosomes, and partly because of a failure of spermiogenesis.
Full Text
The Full Text of this article is available as a PDF (4.1 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abrahamson S, Herskowitz I H, Muller H J. Identification of Half-Translocations Produced by X-Rays in Detaching Attached-X Chromosomes of Drosophila Melanogaster. Genetics. 1956 May;41(3):410–419. doi: 10.1093/genetics/41.3.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cooper K W. Phenotypic Effects of Y Chromosome Hyperploidy in Drosophila Melanogaster, and Their Relation to Variegation. Genetics. 1956 Mar;41(2):242–264. doi: 10.1093/genetics/41.2.242. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dävring L., Sunner M. Female meiosis and embryonic mitosis in Drosophila melanogaster. I. Meiosis and fertilization. Hereditas. 1973;73(1):51–64. doi: 10.1111/j.1601-5223.1973.tb01067.x. [DOI] [PubMed] [Google Scholar]
- Kaufmann B. P., Gay H. The capacity of the fourth chromosome of Drosophila melanogaster to establish end-to-end contacts with the other chromosomes in salivary-gland cells. Chromosoma. 1969;26(4):395–409. doi: 10.1007/BF00326352. [DOI] [PubMed] [Google Scholar]
- Novitski E., Grace D., Strommen C., Puro J. Terminal chromosome attachments. Am J Hum Genet. 1981 Jan;33(1):55–60. [PMC free article] [PubMed] [Google Scholar]
- Tokuyasu K. T., Peacock W. J., Hardy R. W. Dynamics of spermiogenesis in Drosophila melanogaster. VII. Effects of segregation distorter (SD) chromosome. J Ultrastruct Res. 1977 Jan;58(1):96–107. doi: 10.1016/s0022-5320(77)80011-7. [DOI] [PubMed] [Google Scholar]