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. 1988 Sep;60(3):188–195. doi: 10.1136/hrt.60.3.188

Left ventricular volume measured rapidly by oblique magnetic resonance imaging.

S R Underwood 1, C R Gill 1, D N Firmin 1, R H Klipstein 1, R H Mohiaddin 1, R S Rees 1, D B Longmore 1
PMCID: PMC1216552  PMID: 3179134

Abstract

Magnetic resonance measurements of left ventricular volume and ejection fraction based on measurements of area and length in a single oblique plane containing the long axis of the ventricle were compared with measurements made by summing the areas of the chamber in multiple contiguous slices. The multislice technique is known to be accurate, but the single slice technique is much quicker; it takes only nine minutes of acquisition time for both volume and ejection fraction. In 25 normal subjects there was good agreement between the two methods of measuring volume with a mean (SD) difference between measurements of 2.0 (6.6) ml. In 20 patients with previous infarction it was less good with a mean (SD) difference of 4.5 (18.1) ml. The mean (SD) difference of ejection fraction measurements was -0.019 (0.038) in the normal subjects and -0.059 (0.106) in the patients, and the discrepancy between the two techniques was greatest in the patients with a pronounced abnormality of wall motion and low ejection fraction. In a further 25 normal subjects, the agreement between single plane volume measurements in the vertical and horizontal long axis planes was good, indicating that either plane is suitable for rapid measurement. Single plane measurements of left ventricular volume and ejection fraction can be made with the accuracies stated, which are sufficient for routine clinical use except in patients with a pronounced abnormality of wall motion. In combination with measurements of regional wall thickness and motion, previously described, the technique offers a rapid non-invasive assessment of both global and regional left ventricular function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARVIDSSON H. Angiocardiographic determination of left ventricular volume. Acta radiol. 1961 Nov;56:321–339. doi: 10.3109/00016926109172827. [DOI] [PubMed] [Google Scholar]
  2. Bland J. M., Altman D. G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986 Feb 8;1(8476):307–310. [PubMed] [Google Scholar]
  3. Buckwalter K. A., Aisen A. M., Dilworth L. R., Mancini G. B., Buda A. J. Gated cardiac MRI: ejection-fraction determination using the right anterior oblique view. AJR Am J Roentgenol. 1986 Jul;147(1):33–37. doi: 10.2214/ajr.147.1.33. [DOI] [PubMed] [Google Scholar]
  4. CHAPMAN C. B., BAKER O., REYNOLDS J., BONTE F. J. Use of biplane cinefluorography for measurement of ventricular volume. Circulation. 1958 Dec;18(6):1105–1117. doi: 10.1161/01.cir.18.6.1105. [DOI] [PubMed] [Google Scholar]
  5. DODGE H. T., SANDLER H., BALLEW D. W., LORD J. D., Jr The use of biplane angiocardigraphy for the measurement of left ventricular volume in man. Am Heart J. 1960 Nov;60:762–776. doi: 10.1016/0002-8703(60)90359-8. [DOI] [PubMed] [Google Scholar]
  6. Dodge H. T., Sandler H., Baxley W. A., Hawley R. R. Usefulness and limitations of radiographic methods for determining left ventricular volume. Am J Cardiol. 1966 Jul;18(1):10–24. doi: 10.1016/0002-9149(66)90191-3. [DOI] [PubMed] [Google Scholar]
  7. Just H., Holubarsch C., Friedburg H. Estimation of left ventricular volume and mass by magnetic resonance imaging: comparison with quantitative biplane angiocardiography. Cardiovasc Intervent Radiol. 1987;10(1):1–4. doi: 10.1007/BF02583296. [DOI] [PubMed] [Google Scholar]
  8. Kennedy J. W., Trenholme S. E., Kasser I. S. Left ventricular volume and mass from single-plane cineangiocardiogram. A comparison of anteroposterior and right anterior oblique methods. Am Heart J. 1970 Sep;80(3):343–352. doi: 10.1016/0002-8703(70)90099-2. [DOI] [PubMed] [Google Scholar]
  9. Longmore D. B., Klipstein R. H., Underwood S. R., Firmin D. N., Hounsfield G. N., Watanabe M., Bland C., Fox K., Poole-Wilson P. A., Rees R. S. Dimensional accuracy of magnetic resonance in studies of the heart. Lancet. 1985 Jun 15;1(8442):1360–1362. doi: 10.1016/s0140-6736(85)91786-6. [DOI] [PubMed] [Google Scholar]
  10. Markiewicz W., Sechtem U., Kirby R., Derugin N., Caputo G. C., Higgins C. B. Measurement of ventricular volumes in the dog by nuclear magnetic resonance imaging. J Am Coll Cardiol. 1987 Jul;10(1):170–177. doi: 10.1016/s0735-1097(87)80176-6. [DOI] [PubMed] [Google Scholar]
  11. Møgelvang J., Thomsen C., Mehlsen J., Bräckle G., Stubgaard M., Henriksen O. Evaluation of left ventricular volumes measured by magnetic resonance imaging. Eur Heart J. 1986 Dec;7(12):1016–1021. doi: 10.1093/oxfordjournals.eurheartj.a062010. [DOI] [PubMed] [Google Scholar]
  12. Nayler G. L., Firmin D. N., Longmore D. B. Blood flow imaging by cine magnetic resonance. J Comput Assist Tomogr. 1986 Sep-Oct;10(5):715–722. doi: 10.1097/00004728-198609000-00001. [DOI] [PubMed] [Google Scholar]
  13. Osbakken M., Yuschok T. Evaluation of ventricular function with gated cardiac magnetic resonance imaging. Cathet Cardiovasc Diagn. 1986;12(3):156–160. [PubMed] [Google Scholar]
  14. Sandler H., Dodge H. T. The use of single plane angiocardiograms for the calculation of left ventricular volume in man. Am Heart J. 1968 Mar;75(3):325–334. doi: 10.1016/0002-8703(68)90089-6. [DOI] [PubMed] [Google Scholar]
  15. Sechtem U., Pflugfelder P. W., Gould R. G., Cassidy M. M., Higgins C. B. Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging. Radiology. 1987 Jun;163(3):697–702. doi: 10.1148/radiology.163.3.3575717. [DOI] [PubMed] [Google Scholar]
  16. Soloff L. A. On measuring left ventricular volume. Am J Cardiol. 1966 Jul;18(1):2–5. doi: 10.1016/0002-9149(66)90189-5. [DOI] [PubMed] [Google Scholar]
  17. Stratemeier E. J., Thompson R., Brady T. J., Miller S. W., Saini S., Wismer G. L., Okada R. D., Dinsmore R. E. Ejection fraction determination by MR imaging: comparison with left ventricular angiography. Radiology. 1986 Mar;158(3):775–777. doi: 10.1148/radiology.158.3.3945753. [DOI] [PubMed] [Google Scholar]
  18. Underwood S. R., Firmin D. N., Klipstein R. H., Rees R. S., Longmore D. B. Magnetic resonance velocity mapping: clinical application of a new technique. Br Heart J. 1987 May;57(5):404–412. doi: 10.1136/hrt.57.5.404. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Underwood S. R., Klipstein R. H., Firmin D. N., Fox K. M., Poole-Wilson P. A., Rees R. S., Longmore D. B. Magnetic resonance assessment of aortic and mitral regurgitation. Br Heart J. 1986 Nov;56(5):455–462. doi: 10.1136/hrt.56.5.455. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Underwood S. R., Rees R. S., Savage P. E., Klipstein R. H., Firmin D. N., Fox K. M., Poole-Wilson P. A., Longmore D. B. Assessment of regional left ventricular function by magnetic resonance. Br Heart J. 1986 Oct;56(4):334–340. doi: 10.1136/hrt.56.4.334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Utz J. A., Herfkens R. J., Heinsimer J. A., Bashore T., Califf R., Glover G., Pelc N., Shimakawa A. Cine MR determination of left ventricular ejection fraction. AJR Am J Roentgenol. 1987 May;148(5):839–843. doi: 10.2214/ajr.148.5.839. [DOI] [PubMed] [Google Scholar]
  22. Walton S., Yiannikas J., Jarritt P. H., Brown N. J., Swanton R. H., Ell P. J. Phasic abnormalities of left ventricular emptying in coronary artery disease. Br Heart J. 1981 Sep;46(3):245–253. doi: 10.1136/hrt.46.3.245. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Wynne J., Green L. H., Mann T., Levin D., Grossman W. Estimation of left ventricular volumes in man from biplane cineangiograms filmed in oblique projections. Am J Cardiol. 1978 Apr;41(4):726–732. doi: 10.1016/0002-9149(78)90824-x. [DOI] [PubMed] [Google Scholar]

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