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. 1996 Jul 15;317(Pt 2):343–346. doi: 10.1042/bj3170343

Phosphatidylserine-mediated adhesion of T-cells to endothelial cells.

J Qu 1, L A Conroy 1, J H Walker 1, F B Wooding 1, J A Lucy 1
PMCID: PMC1217493  PMID: 8713056

Abstract

Phosphatidylserine was exposed on the surface of human umbilical endothelial cells (ECV304) a few minutes after adding thrombin in vitro, as monitored by prothrombinase assays with and without annexin V. Jurkat T cells adhered to the thrombin-treated cells. The adhesion was inhibited by annexin V, indicating that it was mediated by exposed phosphatidylserine on the endothelial cells.

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Selected References

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