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. 1998 Jun 1;332(Pt 2):297–301. doi: 10.1042/bj3320297

A novel transforming growth factor beta2 antisense transcript in mammalian lung.

R K Coker 1, G J Laurent 1, K Dabbagh 1, J Dawson 1, R J McAnulty 1
PMCID: PMC1219481  PMID: 9601055

Abstract

Transforming growth factor (TGF) beta2 gene expression was examined in murine, rat and human lung by in situ hybridization with riboprobes. Hybridization signal was observed in a variety of cells with the sense probe, and Northern-blot analysis with this probe demonstrated the presence of a novel 3.5 kb transcript. This first report suggesting the existance of a natural TGFbeta2 antisense transcript raises the possibility that such a transcript may play a role in regulating TGFbeta2 production.

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Selected References

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