Skip to main content
Journal of Cancer Research and Clinical Oncology logoLink to Journal of Cancer Research and Clinical Oncology
. 1996 Oct;122(10):638–642. doi: 10.1007/BF01221198

Signal Transduction into the Nucleus: Fifth Colloquium on Cellular Signal Transduction

Heidelberg, Germany, January 1996

F Marks 1,, P Angel 1,2
PMCID: PMC12201281  PMID: 8879263

The content is available as a PDF (555.6 KB).

Footnotes

The next colloquium on cellular signal transduction (topic: Signal transduction and mechanisms of cell death) will be on January 17, 1997

References

  1. Angel P, Karin M (1991) The role of Jun, fos and the AP-1 complex in cell proliferation and transformation. Biochim Biophys Acta 1072: 129–157 [DOI] [PubMed] [Google Scholar]
  2. Bischoff FR, Krebber H, Kempf T, Ponstingl H (1995a) Human RanGTPase activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport. Proc Natl Acad Sci USA 92:1749–1753 [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bischoff FR, Krebber H, Smirnova E, Dong W, Ponsting, H (1995b) Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1. EMBO J 14:705–715 [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Blendy JA, Kaestner KH, Schmid W, Gass P, Schütz G (1996a) Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform. EMBO J 15 1098–1106 [PMC free article] [PubMed] [Google Scholar]
  5. Blendy JA, Kaestner KH, Weinbauer F, Nieschlag E, Schütz G (1996b) Severe impairment of spermatogenesis in mice lacking the CREM gene. Nature 380:162–165 [DOI] [PubMed] [Google Scholar]
  6. Bohmann D, Ellis MC, Staszewski LM, Mlodzik M (1994)Drosophila Jun mediates Ras-dependent photoreceptor determination. Cell 78: 973–986 [DOI] [PubMed] [Google Scholar]
  7. Cole TJ, Blendy JA, Monaghan AP, Krieglstein K, Schmid W, Aguzzi A, Fantuzzi G, Hummler E, Unsicker K, Schütz G (1995) Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev 9:1608–1621 [DOI] [PubMed] [Google Scholar]
  8. Dam H van, Wilhelm D, Herr I, Steffen A, Herrlich P, Angel P (1995) ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J 14:1798–1811 [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gack S, Vallon R, Schaper J, Rüther U, Angel P (1994) Phenotypic alterations in Fos-transgenic mice correlate with changes in Fos/Jun-dependent collagenase type I expression. J Biol Chem 269: 10363–10369 [PubMed] [Google Scholar]
  10. Gstaiger M, Georgiev O, Leeuwen H van, Vliet P van der, Schaffner W (1996) The B-cell coactivator Bob1 shows DNA sequence dependent complex formation with Oct-1/Oct-2 factors leading to differential promoter activation. EMBO J (in press) [PMC free article] [PubMed]
  11. Hemmann U, Gerhartz C, Heesel B, Sasse J, Kurapkat G, Grötzinger J, Wollmer A, Zhong Z, Darnell JE Jr., Graeve L, Heinrich PC, Horn F (1966) Differential activation of APRF/Stat3 and Stat1 via the cytoplasmic domain of the interleukin-6 signal transducer gp 130.2. Src homology SH2 domains define the specificity of STAT factor activation. J Biol Chem (in press) [DOI] [PubMed]
  12. Los M, Craen M van de, Penning CL, Schenk H, Westendorp M, Baeuerle PA, Dröge W, Krammer PH, Fiers W, Schulze-Osthoff K (1995) Requirement of an ICE/Ced-3 protease for Fas/APO-1-mediated apoptosis. Nature 371:81–83 [DOI] [PubMed] [Google Scholar]
  13. Lütticken C, Wegenka UM, Yuan J, Buschmann J, Schindler C, Ziemiecki A, Harpur AG, Wilks AF, Yasukawa K, Taga T, Kishimoto T, Barbieri G, Pellegrini S, Sendtner M, Heinrich PC, Horn F (1994) Association of transcription factor APRF and protein kinase JAK1 with the IL-6 signal transducer gp130. Science 263:89–92 [DOI] [PubMed] [Google Scholar]
  14. Margolin JF, Friedman JR, Meyer WK, Vissing H, Thiesen HJ, Rauscher F (1994) Krüppel-associated boxes are potent transcriptional repression domains. Proc Natl Acad Sci USA 91: 4509–4513 [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Papavassiliou AG, Treier M, Bohmann D (1995) Intramolecular signal transduction in c-Jun. EMBO J 14:2014–2019 [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Pfisterer P, Annweiler A, Ullmer C, Corcoran LM, Wirth T (1994) Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities. EMBO J 13: 1654–1663 [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Pfisterer P, Zwilling S, Hess J, Wirth T (1995) Functional characterization of the murine homolog of the B-cell-specific coactivator BOB-1/OBF.1. J Biol Chem 270:1–11 [DOI] [PubMed] [Google Scholar]
  18. Pyerin W, Ackermann K, Lorenz P (1996) Casein kinases. In: Marks F (ed) Protein phosphorylation VCH Weinheim (in press) [Google Scholar]
  19. Schnapp A, Grummt I (1992) Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase. J Biol Chem 266: 24588–24595 [PubMed] [Google Scholar]
  20. Schreiber M, Baumann B, Cotten M, Angel P, Wagner EF (1995) Fos is an essential component of the mammalian UV response. EMBO J 14:5338–5349 [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Schulze-Osthoff K, Walczak H, Dröge W, Krammer PH (1994) Cell nucleus and DNA fragmentation are not required for apoptosis. J cell Biol 127:15–20 [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Seldin DC, Leder P (1995) Casein kinase IIα transgene-induced murine lymphoma: Relation to Theileriosis in cattle. Science 267:894–897 [DOI] [PubMed] [Google Scholar]
  23. Voit R, Kuhn A, Sander EE, Grummt I (1995) Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF. Nucleic Acids Res 23: 2593–2599 [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Westendorp M, Shatrov V, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer PH, Dröge W, Lehmann V (1995) HIV-1 Tat potentiates TNF-induced NF-κB activation and cytotoxicity by altering the cellular redox state. EMBO J 14:546–554 [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Zeiner M, Gehring U (1995) A protein that interacts with members of the nuclear hormone receptor family: identification and cDNA cloning. Proc Natl Acad Sci USA 92:11465–11469 [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Cancer Research and Clinical Oncology are provided here courtesy of Springer

RESOURCES