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. 2025 Jun 16;16(13):2559–2560. doi: 10.1021/acschemneuro.5c00409

Correction to “Discovery of ONO-2920632 (VU6011887): A Highly Selective and CNS Penetrant TREK‑2 (TWIK-Related K+ Channel 2) Preferring Activator In Vivo Tool Compound”

Kentaro Yashiro, Yuzo Iwaki, Hirohito Urata, Masaya Kokubo, Takahiro Mori, Yoko Sekioka, Koichi Isami, Junya Kato, Joshua Wieting, Kevin M McGowan, Thomas M Bridges, Olivier Boutaud, Darren W Engers, Jerod S Denton, Haruto Kurata ✉, Craig W Lindsley ✉
PMCID: PMC12226813  PMID: 40523247

In the original article, there was an error in the structure of compound 20. The correct structure is given below.graphic file with name cn5c00409_0001.jpg

Also the chemical name in the text is modified from “[1,2,4]­triazolo­[4,3- b]­pyridine core” to “[1,2,4]­triazolo­[4,3- a]­pyridine core”.

In the original article, there is an error in Figure S5. A corrected version of the Supporting Information has been submitted with the corrected Figure S5.

Supplementary Material

cn5c00409_si_001.pdf (1.4MB, pdf)

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acschemneuro.5c00409.

  • Additional experimental details; methods for the synthesis and characterization of all compounds (1H NMR, 13C NMR, 2-D NMR, HRMS); in vitro and in vivo DMPK protocols and Supporting Figures (PDF)

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

cn5c00409_si_001.pdf (1.4MB, pdf)

Articles from ACS Chemical Neuroscience are provided here courtesy of American Chemical Society

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