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. 2003 Mar 1;370(Pt 2):713–717. doi: 10.1042/BJ20020638

Two Dictyostelium ribosomal proteins act as RNases for specific classes of mRNAs.

Giorgio Mangiarotti 1
PMCID: PMC1223170  PMID: 12392449

Abstract

Phosphorylation of ribosomal protein S6 leads to the stabilization of pre-spore specific mRNAs during development of Dictyostelium discoideum. The purification of S6 kinase has allowed the identification of protein S11 as the mRNase specific for pre-spore mRNAs. Methylation of ribosomal protein S31 leads to the destabilization of ribosomal protein mRNAs. The purification of S31 methyltransferase has allowed the identification of protein S29 as the mRNAse specific for ribosomal protein mRNAs.

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Selected References

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